Results 41 to 50 of about 1,608,385 (286)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Up-to-Date Aspects of Antihypertensive Therapy from the Viewpoint of Cardioand Nephroprotective Action: Olmesartan

Антибиотики и Химиотерапия, 2020
The literature data on possible optimization of the arterial hypertension management with organoprotective antihypertensive agents are reviewed. Olmesartan is one of the most thoroughly investigated agents blocking the receptors to angiotensin-II that ...
A. G. Evdokimova, Yu. V. Ryzhova
doaj  

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Gingival Enlargement in Antihypertensive Medication

Journal of Nepal Medical Association, 2009
Introduction: Drug-induced gingival enlargement is a well documented side effect with the use of phenytoin, cyclosporine and calcium channel blockers. The prevalence of gingival enlargement induced by calcium channel blockers is uncertain.
Shaili Pradhan, P Mishra
doaj   +1 more source

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Antihypertensive agents safety during pregnancy

RUDN Journal of Medicine, 2011
The article discusses pregnancy course and labor outcomes in women with chronic hypertension. We divided all pregnant into two groups in dependence on the kind of antihypertensive treatment. The main group treatment was nebivalol monotherapy, the control
E V Karpova, A A Orazmuradov, I A Litvinenko, U A Andreeva, E N Kryukova, T V Bratchikova, V A Lusov   +6 more
doaj  

Synthesis of Benzimidazole Derivatives: As Anti-hypertensive Agents

E-Journal of Chemistry, 2006
A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. This N-(biphenyl methyl) imidazoles e.g. 5-substituted (amino) -2- phenyl-1-(2ʼcarboxy biphenyl-4-yl) benzimidazoles differ from the previously reported and related ...
Jat Rakesh Kumar, Jat Jawahar L., D. P. Pathak   +2 more
doaj   +1 more source

No influence of antihypertensive agents on plasma free metanephrines [PDF]

, 2016
Background: Hypertension can be the predominant sign of pheochromocytoma (PCC) and sympathetic paraganglioma (sPGL) and screening for PCC/sPGL is often performed in patients who are already being treated with antihypertensive agents. There is very little
Links, Thera P., Horst-Schrivers, van der, Anouk, de Jong, Wilhelmina H. A., van Faassen, Martijn; id_orcid, Kema, Ido P., Osinga, Thamara E., Dullaart, Robin P. F., Kema, Ido P.; id_orcid, Kerstens, Michiel N., van Faassen, Martijn   +9 more
core   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Impact of Antihypertensive Treatment on Maternal and Perinatal Outcomes in Pregnancy Complicated by Chronic Hypertension: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Chronic hypertension complicates around 3% of all pregnancies. There is evidence that treating severe hypertension reduces maternal morbidity.
Louise M. Webster, Frances Conti‐Ramsden, Paul T. Seed, Andrew J. Webb, Catherine Nelson‐Piercy, Lucy C. Chappell   +5 more
doaj   +1 more source