Results 41 to 50 of about 3,333,027 (254)
Permutation inference methods for multivariate meta-analysis [PDF]
Biometrics 2020;76(1):337-347, 2018 Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies heterogeneities.
arxiv +1 more source
Scientific Reports, 2023 Renin-angiotensin system inhibitors (RASi), particularly angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), are commonly used in the treatment of hypertension and are recommended for kidney protection ...
Qiao Gao +4 more
doaj +1 more source
Targeted-BEHRT: Deep learning for observational causal inference on longitudinal electronic health records [PDF]
arXiv, 2022 Observational causal inference is useful for decision making in medicine when randomized clinical trials (RCT) are infeasible or non generalizable. However, traditional approaches fail to deliver unconfounded causal conclusions in practice. The rise of "doubly robust" non-parametric tools coupled with the growth of deep learning for capturing rich ...
arxiv
Outlier detection and influence diagnostics in network meta-analysis [PDF]
Res Synth Methods 2020;11(6):891-902, 2019 Network meta-analysis has been gaining prominence as an evidence synthesis method that enables the comprehensive synthesis and simultaneous comparison of multiple treatments. In many network meta-analyses, some of the constituent studies may have markedly different characteristics from the others, and may be influential enough to change the overall ...
arxiv +1 more source
Modern combination antihypertensive pharmacotherapy [PDF]
Системные гипертензии, 2018 Achievement of target blood pressure levels is one of the main issues in antihypertensive pharmacotherapy. The article presents updated 2018 European Guidelines recommendations on target blood pressure levels in antihypertensive therapy and combined ...
O A Mubarakshina +2 more
doaj +1 more source
2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents [PDF]
, 2016 Increasing prevalence of hypertension (HTN) in children and adolescents has become a significant public health issue driving a considerable amount of research.
Agabiti-Rosei, Enrico +18 more
core +1 more source
A computational framework for pharmaco-mechanical interactions in arterial walls using parallel monolithic domain decomposition methods [PDF]
arXiv, 2023 A computational framework is presented to numerically simulate the effects of antihypertensive drugs, in particular calcium channel blockers, on the mechanical response of arterial walls. A stretch-dependent smooth muscle model by Uhlmann and Balzani is modified to describe the interaction of pharmacological drugs and the inhibition of smooth muscle ...
arxiv
Journal of Medical Internet Research, 2016 Background Drug repositioning refers to the process of developing new indications for existing drugs. As a phenotypic indicator of drug response in humans, clinical side effects may provide straightforward signals and unique opportunities for drug ...
Kejian Wang +3 more
semanticscholar +1 more source
Combination therapy in the treatment of hypertension
Drugs in Context, 2018 Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj +1 more source
Antihypertensive agents and risk of Parkinson's disease, essential tremor and dementia : a population-based prospective study (NEDICES) [PDF]
, 2009 Background: Recent interest in antihypertensive agents, especially calcium channel blockers, has been sparked by the notion that these medications may be neuroprotective.
Benito-Leon, Julian +2 more
core +2 more sources