Results 41 to 50 of about 109,974 (359)

Patrones de uso de antihipertensivos en 11.947 pacientes colombianos.

Biomédica: revista del Instituto Nacional de Salud, 2002
El 12,6% de la población colombiana mayor de 15 años es hipertensa. Para conocer sobre el manejo farmacológico de la hipertensión y su comorbilidad, se desarrolló este estudio en 11.947 hipertensos adultos de ambos sexos, en tratamiento durante más de 3 ...
Carlos A. Isaza, Franciso J. Osorio, Giovanny Mesa, Juan C. Moncada   +3 more
doaj   +1 more source

A prospective randomized trial of FK506-based immunosuppression after renal transplantation [PDF]

, 1995
A group of 204 adult patients was entered into a prospective, randomized trial comparing FK506/pred-nisone with FK506/azathioprine/prednisone after renal transplantation between August 1, 1991 and October 11,1992.
Demetris, AJ, Fung, JJ, Hakala, TR, Irish, W, Jordan, ML, McCauley, J, Mitchell, S, Randhawa, P, Scantlebury, VP, Shapiro, R, Simmons, RL, Starzl, TE, Vivas, C   +12 more
core   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

Advanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang, Jianbing Hou, Xin Hu, Nana Hou, Minghao Xu, Yi Du, Jingyang Xu, Yongzhao Wang, Zhuohao Xie, Junbo Shi, Yundong Zhang, Hongjuan Cui   +11 more
wiley   +1 more source

Up-to-Date Aspects of Antihypertensive Therapy from the Viewpoint of Cardioand Nephroprotective Action: Olmesartan

Антибиотики и Химиотерапия, 2020
The literature data on possible optimization of the arterial hypertension management with organoprotective antihypertensive agents are reviewed. Olmesartan is one of the most thoroughly investigated agents blocking the receptors to angiotensin-II that ...
A. G. Evdokimova, Yu. V. Ryzhova
doaj  

Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study

BMJ Open, 2022
Objectives To describe the prescribing trends of antihypertensive drugs in primary care patients and assess the trajectory of antihypertensive drug prescriptions, from first-line to third-line, in patients with hypertension according to changes to the ...
Tibor Schuster, Laurent Azoulay, Julie Rouette, Emily G. McDonald, James M. Brophy   +4 more
doaj   +1 more source

Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study [PDF]

, 2013
Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity.
A Weeke, AJ Ferrari, AJ Mitchell, B Felker, B Ya-Mei, Bruce Guthrie, C Astrup, C Crump, CW Colton, Daniel J Smith, Daniel Martin, DJ Smith, E Koranyi, EH Høyer, F Angst, FG Joseph, Gary McLean, J Johnson, J Langan, JA Mackell, Julie Langan, K Barnett, LM Koran, M De Hert, M De Hert, M De Hert, M Tohen, MJ Fleury, MT Tsuang, N Myles, O Bratfos, P Vestergaard, PA Kurdyak, R Sharma, RM Weinryb, SH Han, Stewart W Mercer, T Callréus, TM Laursen, TM Laursen, U Osby, U Petterson, VMR Carstairs   +42 more
core   +2 more sources

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source

CURRENT TARGET OF ANTIHYPERTENSIVE THERAPY. DATA FROM CLINICAL TRIALS. PART 1

Рациональная фармакотерапия в кардиологии, 2015
Arterial hypertension (HT) takes leading position in the structure of morbidity and mortality among the cardiovascular diseases in the economically developed and developing countries of the world.
V. V. Popov, N. A. Bulanov, G. G. Ivanov
doaj   +3 more sources

Synthesis of Benzimidazole Derivatives: As Anti-hypertensive Agents

E-Journal of Chemistry, 2006
A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. This N-(biphenyl methyl) imidazoles e.g. 5-substituted (amino) -2- phenyl-1-(2ʼcarboxy biphenyl-4-yl) benzimidazoles differ from the previously reported and related ...
Jat Rakesh Kumar, Jat Jawahar L., D. P. Pathak   +2 more
doaj   +1 more source

Medication persistence trajectories among individuals prescribed lipid‐lowering therapy in primary care settings: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to identify distinct trajectories of lipid‐modifying medication (LMM) persistence over time and to explore characteristics associated with each pattern. Methods Using primary care data from IQVIA, we conducted a retrospective cohort study of adults prescribed LMMs between January 2015 and December 2017, with 5 years of follow‐up ...
Zhomart Orman, Jia Wei Koh, Caroline Trin, Zanfina Ademi, Ella Zomer, Danielle Berkovic, Jenni Ilomaki, J. Simon Bell, Danny Liew, Christopher M. Reid, Sean Lybrand, Brittany Schoeninger, Stella Talic   +12 more
wiley   +1 more source