Results 51 to 60 of about 107,975 (358)

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia [PDF]

open access: yes, 2011
OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral ...
Bodmer, Michael   +4 more
core   +2 more sources

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan   +19 more
wiley   +1 more source

CURRENT TARGET OF ANTIHYPERTENSIVE THERAPY. DATA FROM CLINICAL TRIALS. PART 1

open access: yesРациональная фармакотерапия в кардиологии, 2015
Arterial hypertension (HT) takes leading position in the structure of morbidity and mortality among the cardiovascular diseases in the economically developed and developing countries of the world.
V. V. Popov, N. A. Bulanov, G. G. Ivanov
doaj   +3 more sources

Antihypertensive agents safety during pregnancy

open access: yesRUDN Journal of Medicine, 2011
The article discusses pregnancy course and labor outcomes in women with chronic hypertension. We divided all pregnant into two groups in dependence on the kind of antihypertensive treatment. The main group treatment was nebivalol monotherapy, the control
E V Karpova   +6 more
doaj  

PRESCRIBING OF ANTIHYPERTENSIVE AGENTS IN PUBLIC PRIMARY CARE CLINICS – IS IT IN ACCORDANCE WITH CURRENT EVIDENCE? [PDF]

open access: yesMalaysian Family Physician, 2010
Background: Large population surveys in Malaysia have consistently shown minimal improvement of blood pressure control rates over the last 10 years. Poor adherence to antihypertensive medication has been recognized as a major reason for poor control of ...
SAJARI J   +7 more
doaj  

Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study

open access: yesBMJ Open, 2022
Objectives To describe the prescribing trends of antihypertensive drugs in primary care patients and assess the trajectory of antihypertensive drug prescriptions, from first-line to third-line, in patients with hypertension according to changes to the ...
Tibor Schuster   +4 more
doaj   +1 more source

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome [PDF]

open access: yes, 2008
Background: Progressive enlargement of the aortic root, leading to dissection, is the main cause of premature death in patients with Marfan's syndrome. Recent data from mouse models of Marfan's syndrome suggest that aortic-root enlargement is caused by ...
Brooke, Benjamin S.   +5 more
core   +2 more sources

Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core

open access: yesAsian Journal of Organic Chemistry, EarlyView.
An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos   +6 more
wiley   +1 more source

Pharmacogenetic Tests in the Nephrological Clinic

open access: yesPočki, 2016
Selection of antihypertensive agents using pharmacogenetic tests and individual tolerance is essential in practical nephrology. Antihypertensive first-line drugs are metabolized through various CYP isoforms (CYP2D6, CYP2C9, CYP2C19 and CYP3A4/5).
D.D. Ivanov, O.O. Melnik
doaj   +1 more source

Changes in kidney function in a population with essential hypertension in real life settings [PDF]

open access: yes, 2017
Introduction. Hypertension has been identified as one of the commonest modifiable determinants for chronic kidney disease progression. A variety of antihypertensive drugs are available and their effect on kidney function has been investigated by a ...
Haidich, Anna-Bettina   +6 more
core  

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