Results 71 to 80 of about 3,282,224 (215)

CURRENT TARGET OF ANTIHYPERTENSIVE THERAPY. DATA FROM CLINICAL TRIALS. PART 2

open access: yesРациональная фармакотерапия в кардиологии, 2015
Arterial hypertension (HT) takes leading position in the structure of morbidity and mortality among the cardiovascular diseases in the economically developed and developing countries of the world.
V. V. Popov, N. A. Bulanov, G. G. Ivanov
doaj   +3 more sources

Antihypertensive agents safety during pregnancy

open access: yesRUDN Journal of Medicine, 2011
The article discusses pregnancy course and labor outcomes in women with chronic hypertension. We divided all pregnant into two groups in dependence on the kind of antihypertensive treatment. The main group treatment was nebivalol monotherapy, the control
E V Karpova   +6 more
doaj  

Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study

open access: yesBMJ Open, 2022
Objectives To describe the prescribing trends of antihypertensive drugs in primary care patients and assess the trajectory of antihypertensive drug prescriptions, from first-line to third-line, in patients with hypertension according to changes to the ...
Tibor Schuster   +4 more
doaj   +1 more source

Generating Drug Repurposing Hypotheses through the Combination of Disease-Specific Hypergraphs [PDF]

open access: yesarXiv, 2023
The drug development pipeline for a new compound can last 10-20 years and cost over 10 billion. Drug repurposing offers a more time- and cost-effective alternative. Computational approaches based on biomedical knowledge graph representations have recently yielded new drug repurposing hypotheses.
arxiv  

Synthesis and characterization of quinazoline derivatives: search for hybrid molecule as diuretic and antihypertensive agents

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2014
To explore the pharmacological and structure–activity relationship of a series of N-substituted-(4-oxo-2-substituted-phenylquinazolin-3-(4H)-yl), substituted benzene sulfonamide derivatives (1–25) were synthesized from substituted anthranilic acids ...
Mujeeb Ur Rahman   +4 more
semanticscholar   +1 more source

CURRENT TARGET OF ANTIHYPERTENSIVE THERAPY. DATA FROM CLINICAL TRIALS. PART 1

open access: yesРациональная фармакотерапия в кардиологии, 2015
Arterial hypertension (HT) takes leading position in the structure of morbidity and mortality among the cardiovascular diseases in the economically developed and developing countries of the world.
V. V. Popov, N. A. Bulanov, G. G. Ivanov
doaj   +3 more sources

How do antihypertensive drugs work? Insights from studies of the renal regulation of arterial blood pressure.

open access: yesFrontiers in Physiology, 2016
Though antihypertensive drugs have been in use for many decades, the mechanisms by which they act chronically to reduce blood pressure remain unclear.
Holly Digne-Malcolm   +2 more
doaj   +1 more source

In vivo study of the antihypertensive effect of bidara leaf (Ziziphus spina-christi) during pregnancy

open access: yesMedisains, 2021
Background: Bidara is drought tolerant and very easy to grow in tropical climates such as Indonesia. Bidara contains a combination of calcium, potassium, and magnesium, and active flavonoid compounds, and antioxidant activity that play a role in ...
Tasya Nurlaila Dilla   +2 more
doaj   +1 more source

Relationship between antihypertensive medications and cognitive impairment: Part II. Review of Physiology and animal studies [PDF]

open access: yes, 2016
Purpose of Review There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHM) and dementia risk are
Carlson, MC   +4 more
core   +1 more source

Meta‐analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index

open access: yesBritish Journal of Clinical Pharmacology, 2013
AIMS Brachial systolic blood pressure (bSBP) exceeds aortic pressure by a variable amount, and estimated central systolic blood pressure (cSBP) may be a better indicator of cardiovascular risk than bSBP. We undertook a systematic review and meta‐analysis
C. Manisty, A. Hughes
semanticscholar   +1 more source

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