Results 1 to 10 of about 3,894,620 (311)
BMC Health Services Research, 2021 Background In 2019, Chinese government launched a nationwide volume-based drug procurement aiming at reducing drug prices and saving drug costs through economies of scale, which aroused widespread attention.
Ying Yang +6 more
doaj +2 more sources
Pharmacomicrobiomics: Exploiting the Drug-Microbiota Interactions in Antihypertensive Treatment
Frontiers in Medicine, 2022 Hypertension is a leading risk factor for cardiovascular diseases and can reduce life expectancy. Owing to the widespread use of antihypertensive drugs, patients with hypertension have improved blood pressure control over the past few decades.
Hui-Qing Chen +7 more
doaj +2 more sources
Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9) [PDF]
Molecules, 2023 Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this paper, a novel compound known as 221s (2,9), which includes tanshinol, borneol and a mother nucleus of ACEI, was synthesized by condensation esterification ...
Bei Qin +12 more
doaj +2 more sources
Antihypertensive drug use and prostate cancer-specific mortality in Finnish men.
PLoS ONE, 2020 The aim of this study was to investigate pre- and post-diagnostic use of antihypertensive drugs on prostate cancer (PCa)-specific survival and the initiation of androgen deprivation therapy (ADT).
Aino Siltari +5 more
doaj +2 more sources
Impact of COVID-19 epidemic on antihypertensive drug treatment disruptions: results from a nationwide interrupted time-series analysis [PDF]
Frontiers in Pharmacology, 2023 Background: The COVID-19 epidemic has disrupted care and access to care in many ways. It was accompanied by an excess of cardiovascular drug treatment discontinuations.
Clément Mathieu +4 more
doaj +2 more sources
PLoS Medicine, 2022 Background Epidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk.
J. Yarmolinsky +22 more
semanticscholar +1 more source
Heart, 2022 Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure (BP) reduction is limited. We investigated the antihypertensive drug effects on BP over time and across different participant characteristics.
D. Canoy +11 more
semanticscholar +1 more source
JAMA psychiatry, 2021 Importance Observational studies have reported associations between antihypertensive medication and psychiatric disorders, although the reported direction of association appears to be dependent on drug class.
S. Chauquet +5 more
semanticscholar +1 more source
Narrative update of clinical trials with antihypertensive drugs in children and adolescents
Frontiers in Cardiovascular Medicine, 2022 IntroductionTo date, our knowledge on antihypertensive pharmacological treatment in children and adolescents is still limited because there are few randomized clinical trials (CTs), hampering appropriate management.
Josep Redon +7 more
doaj +1 more source
Expert Opinion on Drug Metabolism & Toxicology, 2021 Introduction Hypertensive disorders of pregnancy (HDP) are rising in prevalence, and increase risk of adverse maternal and fetal outcomes. Physiologic changes occur during pregnancy that alter drug pharmacokinetics.
Ian R Mulrenin +6 more
semanticscholar +1 more source