Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9) [PDF]
Molecules, 2023 Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this paper, a novel compound known as 221s (2,9), which includes tanshinol, borneol and a mother nucleus of ACEI, was synthesized by condensation esterification ...
Bei Qin +12 more
doaj +2 more sources
BMC Health Services Research, 2021 Background In 2019, Chinese government launched a nationwide volume-based drug procurement aiming at reducing drug prices and saving drug costs through economies of scale, which aroused widespread attention.
Ying Yang +6 more
doaj +2 more sources
Pharmacomicrobiomics: Exploiting the Drug-Microbiota Interactions in Antihypertensive Treatment
Frontiers in Medicine, 2022 Hypertension is a leading risk factor for cardiovascular diseases and can reduce life expectancy. Owing to the widespread use of antihypertensive drugs, patients with hypertension have improved blood pressure control over the past few decades.
Hui-Qing Chen +7 more
doaj +2 more sources
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]
HYPERTENSION, 2016 Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H. +6 more
core +2 more sources
Antihypertensive drug use and prostate cancer-specific mortality in Finnish men.
PLoS ONE, 2020 The aim of this study was to investigate pre- and post-diagnostic use of antihypertensive drugs on prostate cancer (PCa)-specific survival and the initiation of androgen deprivation therapy (ADT).
Aino Siltari +5 more
doaj +2 more sources
Antihypertensive drug treatment changes in the general population: the CoLaus study. [PDF]
BMC Pharmacology and Toxicology, 2014 BACKGROUND: Changes in antihypertensive drug treatment are paramount in the adequate management of patients with hypertension, still, there is little information regarding changes in antihypertensive drug treatment in Switzerland.
Christe, V. +3 more
core +3 more sources
Impact of COVID-19 epidemic on antihypertensive drug treatment disruptions: results from a nationwide interrupted time-series analysis [PDF]
Frontiers in Pharmacology, 2023 Background: The COVID-19 epidemic has disrupted care and access to care in many ways. It was accompanied by an excess of cardiovascular drug treatment discontinuations.
Clément Mathieu +4 more
doaj +2 more sources
Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level [PDF]
HYPERTENSION, 2017 Tatsuya Maruhashi +44 more
openalex +2 more sources
Extensive ischemic gastroduodenal necrosis caused by antihypertensive drug overdose in a young man. [PDF]
Clin Case Rep, 2023 Yuan T, Sun J, Ma Q.
europepmc +3 more sources
Heart, 2022 Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure (BP) reduction is limited. We investigated the antihypertensive drug effects on BP over time and across different participant characteristics.
D. Canoy +11 more
semanticscholar +1 more source