Results 1 to 10 of about 3,910,453 (241)

Pharmacomicrobiomics: Exploiting the Drug-Microbiota Interactions in Antihypertensive Treatment

Frontiers in Medicine, 2022
Hypertension is a leading risk factor for cardiovascular diseases and can reduce life expectancy. Owing to the widespread use of antihypertensive drugs, patients with hypertension have improved blood pressure control over the past few decades.
Hui-Qing Chen, Jin-Yu Gong, Kai Xing, Mou-Ze Liu, Mou-Ze Liu, Huan Ren, Jian-Quan Luo, Jian-Quan Luo   +7 more
doaj   +2 more sources

The impact of “4 + 7” volume-based drug procurement on the volume, expenditures, and daily costs of antihypertensive drugs in Shenzhen, China: an interrupted time series analysis

BMC Health Services Research, 2021
Background In 2019, Chinese government launched a nationwide volume-based drug procurement aiming at reducing drug prices and saving drug costs through economies of scale, which aroused widespread attention.
Ying Yang, Ruiwen Tong, Shicheng Yin, Lining Mao, Luxinyi Xu, Siyu Hao, Zongfu Mao   +6 more
doaj   +2 more sources

Antihypertensive drug therapy [PDF]

Annals of Translational Medicine, 2018
Lifestyle measures plus antihypertensive drug therapy should be used to treat adults with hypertension (1-4). Adults with clinical cardiovascular disease (coronary heart disease, heart failure, and stroke) should have their blood pressure reduced below 130/80 mmHg for secondary prevention of recurrent cardiovascular disease events (4).
Wilbert S. Aronow
openaire   +4 more sources

Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]

HYPERTENSION, 2016
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H., Dominiczak, Anna F., Mccallum, Linsay, Muir, Scott, Padmanabhan, Sandosh, Smith, Daniel J., Touyz, Rhian M.   +6 more
core   +2 more sources

Antihypertensive drug treatment changes in the general population: the CoLaus study. [PDF]

BMC Pharmacology and Toxicology, 2014
BACKGROUND: Changes in antihypertensive drug treatment are paramount in the adequate management of patients with hypertension, still, there is little information regarding changes in antihypertensive drug treatment in Switzerland.
Christe, V., Marques-Vidal, P., Vollenweider, P., Waeber, G.   +3 more
core   +3 more sources

I Brazilian Position Paper on Antihypertensive Drug Combination

Arquivos Brasileiros de Cardiologia, 2014
Arterial hypertension (AH) is a highly prevalent disease, and is a major cardiovascular (CV) risk factor1; therefore, achieving blood pressure (BP) control goals as soon as possible is paramount to reduce that risk2.
Rui Póvoa, Weimar Kunz Sebba Barroso, Andréa Araújo Brandão, Paulo César Brandão Veiga Jardim, Oswaldo Barroso, Oswaldo Passarelli, João Roberto Gemelli, Audes D. M. Feitosa, Thiago Veiga Jardim, Sérgio Baiocchi Carneiro, Celso Amodeo, Osni Moreira Filho, Armando da Rocha Nogueira, Nelson Siqueira de Morais, Luíz Cesar Nazário Scala, Carolina Gonzaga, Dilma do Socorro Moraes de Souza, Annelise Machado Gomes de Paiva, Marcus Vinícius Bolívar Malachias, Décio Mion, Marco Antônio Mota Gomes, Eduardo Costa Duarte Barbosa, Márcio Gonçalves de Sousa, Henrique Tria Bianco, Francisco Antônio Helfenstein Fonseca, Marcio Kalil, Roberto Dischinger Miranda, Carlos André Uehara, Antônio Felipe Sanjuliani   +28 more
openalex   +2 more sources

Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level [PDF]

HYPERTENSION, 2017
Tatsuya Maruhashi, Junko Soga, Noritaka Fujimura, Naomi Idei, Shinsuke Mikami, Yumiko Iwamoto, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Haruki Hashimoto, Yoshiki Aibara, Farina Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Chikara Goto, Hirofumi Tomiyama, Bonpei Takase, Takahide Kohro, Toru Suzuki, Tomoko Ishizu, Shinichiro Ueda, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Kentaro Watanabe, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Hisao Ikeda, Akira Yamashina, Yukihito Higashi   +44 more
openalex   +2 more sources

Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9)

Molecules, 2023
Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this paper, a novel compound known as 221s (2,9), which includes tanshinol, borneol and a mother nucleus of ACEI, was synthesized by condensation esterification ...
Bei Qin, Lili Yu, Rong Wang, Yimei Tang, Yunmei Chen, Nana Wang, Yixin Zhang, Xiong Tan, Kuan Yang, Bo Zhang, Maofang He, Yuzhen Zhang, Yaqi Hu   +12 more
doaj   +1 more source

Association of Antihypertensive Drug Target Genes With Psychiatric Disorders: A Mendelian Randomization Study.

JAMA psychiatry, 2021
Importance Observational studies have reported associations between antihypertensive medication and psychiatric disorders, although the reported direction of association appears to be dependent on drug class.
S. Chauquet, Zhihong Zhu, M. O’Donovan, J. Walters, N. Wray, Sonia H. Shah   +5 more
semanticscholar   +1 more source

Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials

Heart, 2022
Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure (BP) reduction is limited. We investigated the antihypertensive drug effects on BP over time and across different participant characteristics.
D. Canoy, E. Copland, M. Nazarzadeh, R. Ramakrishnan, Ana-Catarina Pinho-Gomes, A. Salam, J. Dwyer, F. Farzadfar, J. Sundström, M. Woodward, B. Davis, K. Rahimi   +11 more
semanticscholar   +1 more source