Results 1 to 10 of about 93,278 (263)

Antihypertensive drug reduction for treated hypertensive patients during the summer

Clinical and Experimental Hypertension, 2019
Seasonal winter–summer variation in blood pressure (BP) has been reported, but there are few reports on the reduction of antihypertensive medication during the summer. We aimed to investigate the prevalence and details of drug reduction during the summer
Kimika Arakawa, Ai Ibaraki, Yuki Kawamoto, Mitsuhiro Tominaga, Takuya Tsuchihashi   +4 more
doaj   +2 more sources

Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9)

Molecules, 2023
Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this paper, a novel compound known as 221s (2,9), which includes tanshinol, borneol and a mother nucleus of ACEI, was synthesized by condensation esterification ...
Bei Qin, Lili Yu, Rong Wang, Yimei Tang, Yunmei Chen, Nana Wang, Yixin Zhang, Xiong Tan, Kuan Yang, Bo Zhang, Maofang He, Yuzhen Zhang, Yaqi Hu   +12 more
doaj   +1 more source

Narrative update of clinical trials with antihypertensive drugs in children and adolescents

Frontiers in Cardiovascular Medicine, 2022
IntroductionTo date, our knowledge on antihypertensive pharmacological treatment in children and adolescents is still limited because there are few randomized clinical trials (CTs), hampering appropriate management.
Josep Redon, Tomas Seeman, Dénes Pall, Lagle Suurorg, Konstantinos Kamperis, Serap Erdine, Elke Wühl, Giuseppe Mancia   +7 more
doaj   +1 more source

Effect of patient and treatment factors on persistence with antihypertensive treatment: A population-based study.

PLoS ONE, 2021
PurposeTo analyze patterns of antihypertensive drug use among new users in a Southern European population, and identify patient- and treatment-related factors that influence persistence.MethodsThis is a retrospective observational study of new ...
Sara Malo, Isabel Aguilar-Palacio, Cristina Feja, María Jesús Lallana, Javier Armesto, María José Rabanaque   +5 more
doaj   +1 more source

Relationship between doses of antihypertensive drugs and left ventricular mass index changes in hemodialysis patients in a Japanese cohort

Renal Failure, 2021
Left ventricular hypertrophy commonly occurs in dialysis patients and is associated with a risk of developing cardiovascular disease events and all-cause mortality.
Fumiya Kitamura, Makoto Yamaguchi, Takayuki Katsuno, Hironobu Nobata, Shiho Iwagaitsu, Hirokazu Sugiyama, Hiroshi Kinashi, Shogo Banno, Masahiko Ando, Yoko Kubo, Yasumasa Kawade, Iwashima Shigejiro, Yutaka Ito, Takuji Ishimoto, Yasuhiko Ito   +14 more
doaj   +1 more source

Pharmacomicrobiomics: Exploiting the Drug-Microbiota Interactions in Antihypertensive Treatment

Frontiers in Medicine, 2022
Hypertension is a leading risk factor for cardiovascular diseases and can reduce life expectancy. Owing to the widespread use of antihypertensive drugs, patients with hypertension have improved blood pressure control over the past few decades.
Hui-Qing Chen, Jin-Yu Gong, Kai Xing, Mou-Ze Liu, Mou-Ze Liu, Huan Ren, Jian-Quan Luo, Jian-Quan Luo   +7 more
doaj   +1 more source

The impact of “4 + 7” volume-based drug procurement on the volume, expenditures, and daily costs of antihypertensive drugs in Shenzhen, China: an interrupted time series analysis

BMC Health Services Research, 2021
Background In 2019, Chinese government launched a nationwide volume-based drug procurement aiming at reducing drug prices and saving drug costs through economies of scale, which aroused widespread attention.
Ying Yang, Ruiwen Tong, Shicheng Yin, Lining Mao, Luxinyi Xu, Siyu Hao, Zongfu Mao   +6 more
doaj   +1 more source

On the issue of low adherence of patients to antihypertensive therapy: the use of therapeutic drug monitoring of drugs: A review

Consilium Medicum, 2022
Low adherence of patients to antihypertensive therapy remains an urgent problem and is recognized as the main cause of insufficient BP control at the population level.
Marina V. Leonova
doaj   +1 more source

Evaluasi Kerasionalan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap RSUD H. Hanafie Muara Bungo

Indonesian Journal of Pharmaceutical Education, 2022
According to the World Health Organization (WHO), hypertension affects 22% of the world's population. Hypertension is also the cause of death with 23.7% of the total 1.7 million deaths in Indonesia in 2016. Based on the medical record sheet at H. Hanafie
Tri Wasilah, Rasmala Dewi, Deny Sutrisno
doaj   +1 more source

The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis. [PDF]

PLoS Medicine, 2007
BACKGROUND: The purpose of our study was to evaluate the effects of a new reimbursement rule for antihypertensive medication that made thiazides mandatory first-line drugs for newly treated, uncomplicated hypertension. The objective of the new regulation
Atle Fretheim, Kari Håvelsrud, Graeme MacLennan, Doris Tove Kristoffersen, Andrew D Oxman   +4 more
doaj   +1 more source