Results 141 to 150 of about 3,932,256 (404)
Effect of Antihypertensive Drugs on the "Intrinsic" Heart Rate [PDF]
, 1969 A Káldor, P Juvancz
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Clinical Pharmacology &Therapeutics, EarlyView.Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Li‐Wen Huang +6 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang +17 more
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Clinical Pharmacology &Therapeutics, EarlyView.Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik +7 more
wiley +1 more source
Drugs in Context, 2018 Antihypertensive treatment of patients with diabetes should include those drugs with a positive effect on metabolic parameters. Most patients with diabetes require at least two antihypertensive agents.
Margarita SaizSatjes +1 more
doaj +1 more source
Effects of Antihypertensive Drugs on Blood Velocity: Implications for Prevention of Cerebral Vascular Disease [PDF]
, 1977 J. David Spence
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Clinical Pharmacology &Therapeutics, EarlyView.Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum +10 more
wiley +1 more source
Drug Interactions in Patients on Long-term Oral Anticoagulant and Antihypertensive Adrenergic Neuron-blocking Drugs [PDF]
, 1972 Kate J. Starr, J C Petrie
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Clinical Pharmacology &Therapeutics, EarlyView.Hydralazine is a vasodilator typically used in the treatment of resistant hypertension and heart failure. N‐acetyltransferase 2 (NAT2) catalyzes the metabolism of hydralazine into inactive metabolites. NAT2 poor metabolizers (historically referred to as “slow acetylators”) are predicted to have increased plasma hydralazine concentrations compared with ...
Michael T. Eadon +18 more
wiley +1 more source
High-density lipoprotein cholesterol and antihypertensive drugs: the Oslo study. [PDF]
, 1978 Anders Helgeland +4 more
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