Results 171 to 180 of about 93,748 (310)

Network medicine and systems pharmacology approaches to predicting adverse drug effects

British Journal of Pharmacology, EarlyView.
Identifying and understanding the relationships between drug intake and adverse effects that can occur due to inadvertent molecular interactions between drugs and targets is a difficult task, especially considering the numerous variables that can influence the onset of such events.
Alessio Funari, Giulia Fiscon, Paola Paci   +2 more
wiley   +1 more source

Impact of Renin-Angiotensin-Aldosterone System (RAAS) Gene Polymorphism in Essential Hypertension and Antihypertensive Drug Therapy: A Review. [PDF]

Int J Hypertens
Adhikari A, Sharma C, Lhamu Sherpa M, Karaunakran G, Dhakal M, Sharma A.   +5 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Spectrophotometric approach for deconvolving overlapped spectra of antihypertensive drug mixtures using UV detection: an eco-friendly method. [PDF]

BMC Chem
Yenduri S, Prashant KN, Varalakshmi HN.
europepmc   +1 more source

The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and Serratia marcescens. [PDF]

Biomedicines, 2023
Alotaibi HF, Alotaibi H, Darwish KM, Khafagy ES, Abu Lila AS, Ali MAM, Hegazy WAH, Alshawwa SZ.   +7 more
europepmc   +1 more source

Prescription audit of antihypertensive drugs used in stroke patients in a tertiary care teaching hospital

, 2021
Bipin Shaji, Jereena George, Aishwarya Shrestha, Sharon Mary Stanly, Noah M. Bose   +4 more
openalex   +2 more sources

A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea, Frédérique Lefrançois, Matthieu St‐Jean, Anne‐Marie Côté, Marie‐Ève Roy‐Lacroix, Mandy Malick, Pierre‐Luc Mallet, Nadine Sauvé   +7 more
wiley   +1 more source

Genetically proxied therapeutic effect of antihypertensive drug use, breast cancer, and ovarian cancer's risk: a drug-target Mendelian randomization study. [PDF]

BMC Cancer
Dang C, Wang R, Shi Y, Liu P, Wang X, Liu J, Yu X, Jin D, Ma Q.   +8 more
europepmc   +1 more source

The effect of novel antihypertensive drug valsartan on lysozyme aggregation: A combined in situ and in silico study. [PDF]

Heliyon, 2023
Altwaijry N, Almutairi GS, Khan MS, Alokail MS, Alafaleq N, Ali R.   +5 more
europepmc   +1 more source

Differential structural requirements for specific binding of nonpeptide and peptide antagonists to the AT1 angiotensin receptor. Identification of amino acid residues that determine binding of the antihypertensive drug losartan

, 1994
H Ji, Mandy H. M. Leung, Yong Zhang, Kevin Catt, Kathryn Sandberg   +4 more
openalex   +1 more source