Results 11 to 20 of about 3,997,149 (388)

Genetically proxied therapeutic effect of antihypertensive drug use, breast cancer, and ovarian cancer’s risk: a drug-target Mendelian randomization study [PDF]

open access: goldBMC Cancer
Chunxiao Dang   +8 more
openalex   +2 more sources

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

open access: yesPLoS Medicine, 2022
Background Epidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk.
J. Yarmolinsky   +22 more
semanticscholar   +1 more source

Narrative update of clinical trials with antihypertensive drugs in children and adolescents

open access: yesFrontiers in Cardiovascular Medicine, 2022
IntroductionTo date, our knowledge on antihypertensive pharmacological treatment in children and adolescents is still limited because there are few randomized clinical trials (CTs), hampering appropriate management.
Josep Redon   +7 more
doaj   +1 more source

The Impact of Pregnancy on Antihypertensive Drug Metabolism and Pharmacokinetics: Current Status and Future Directions

open access: yesExpert Opinion on Drug Metabolism & Toxicology, 2021
Introduction Hypertensive disorders of pregnancy (HDP) are rising in prevalence, and increase risk of adverse maternal and fetal outcomes. Physiologic changes occur during pregnancy that alter drug pharmacokinetics.
Ian R Mulrenin   +6 more
semanticscholar   +1 more source

Antihypertensive Drug Use Pattern in a Tertiary Care Hospital of Western Region of Nepal: A Cross-Sectional Study

open access: yesJournal of Lumbini Medical College, 2023
Introduction: Assessing antihypertensive drug use pattern always plays an important role to mitigate the burden of hypertension and also helps doctors to prescribe the drugs rationally.
Naresh Karki   +3 more
doaj   +1 more source

Antihypertensive drugs

open access: yesPharmacological Research, 2017
Successful treatment of hypertension is possible with limited side effects given the availability of multiple antihypertensive drug classes. This review describes the various pharmacological classes of antihypertensive drugs, under two major aspects: their mechanisms of action and side effects.
Katie Traylor   +5 more
  +5 more sources

Effect of patient and treatment factors on persistence with antihypertensive treatment: A population-based study.

open access: yesPLoS ONE, 2021
PurposeTo analyze patterns of antihypertensive drug use among new users in a Southern European population, and identify patient- and treatment-related factors that influence persistence.MethodsThis is a retrospective observational study of new ...
Sara Malo   +5 more
doaj   +1 more source

Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: a pharmacogenomics study from the CHARGE consortium [PDF]

open access: yes, 2015
Background Hypertension is a major risk factor for a spectrum of cardiovascular diseases (CVD), including myocardial infarction, sudden death, and stroke.
Arnett, Donna   +53 more
core   +7 more sources

Relationship between doses of antihypertensive drugs and left ventricular mass index changes in hemodialysis patients in a Japanese cohort

open access: yesRenal Failure, 2021
Left ventricular hypertrophy commonly occurs in dialysis patients and is associated with a risk of developing cardiovascular disease events and all-cause mortality.
Fumiya Kitamura   +14 more
doaj   +1 more source

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