Results 11 to 20 of about 3,932,256 (404)

Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]

HYPERTENSION, 2016
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H., Dominiczak, Anna F., Mccallum, Linsay, Muir, Scott, Padmanabhan, Sandosh, Smith, Daniel J., Touyz, Rhian M.   +6 more
core   +2 more sources

Antihypertensive drug treatment changes in the general population: the CoLaus study. [PDF]

BMC Pharmacology and Toxicology, 2014
BACKGROUND: Changes in antihypertensive drug treatment are paramount in the adequate management of patients with hypertension, still, there is little information regarding changes in antihypertensive drug treatment in Switzerland.
Christe, V., Marques-Vidal, P., Vollenweider, P., Waeber, G.   +3 more
core   +3 more sources

Individualization of Antihypertensive Drug Treatment [PDF]

Diabetes Care, 2013
Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation.
Mancia, G, Grassi, G
openaire   +4 more sources

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

PLoS Medicine, 2022
Background Epidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk.
J. Yarmolinsky, V. Díez-Obrero, T. Richardson, M. Pigeyre, J. Sjaarda, G. Paré, V. Walker, E. Vincent, V. Y. Tan, M. Obón-Santacana, D. Albanes, J. Hampe, A. Gsur, H. Hampel, R. Pai, M. Jenkins, S. Gallinger, G. Casey, Wei Zheng, C. Amos, George Davey Smith, R. M. Martin, V. Moreno   +22 more
semanticscholar   +1 more source

Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials

Heart, 2022
Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure (BP) reduction is limited. We investigated the antihypertensive drug effects on BP over time and across different participant characteristics.
D. Canoy, E. Copland, M. Nazarzadeh, R. Ramakrishnan, Ana-Catarina Pinho-Gomes, A. Salam, J. Dwyer, F. Farzadfar, J. Sundström, M. Woodward, B. Davis, K. Rahimi   +11 more
semanticscholar   +1 more source

Association of Antihypertensive Drug Target Genes With Psychiatric Disorders: A Mendelian Randomization Study.

JAMA psychiatry, 2021
Importance Observational studies have reported associations between antihypertensive medication and psychiatric disorders, although the reported direction of association appears to be dependent on drug class.
S. Chauquet, Zhihong Zhu, M. O’Donovan, J. Walters, N. Wray, Sonia H. Shah   +5 more
semanticscholar   +1 more source

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes

Neurology, 2020
Objective We employed Mendelian randomization to explore whether the effects of blood pressure (BP) and BP-lowering through different antihypertensive drug classes on stroke risk vary by stroke etiology.
Marios K. Georgakis, D. Gill, A. Webb, E. Evangelou, P. Elliott, C. Sudlow, A. Dehghan, R. Malik, I. Tzoulaki, M. Dichgans   +9 more
semanticscholar   +1 more source

Preadmission Antihypertensive Drug Use and Sepsis Outcome: Impact of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin Receptor Blockers (ARBs).

Shock, 2020
BACKGROUND Several studies have reported improved sepsis outcomes when certain preadmission antihypertensive drugs, namely, calcium channel blockers (CCBs), are used. This study aims to determine whether preadmission antihypertensive drug use, especially
Ming-Shun Hsieh, Chorng-Kuang How, V. C. Hsieh, Pau-Chung Chen   +3 more
semanticscholar   +1 more source

Antihypertensive drug use and prostate cancer-specific mortality in Finnish men

PLoS ONE, 2020
The aim of this study was to investigate pre- and post-diagnostic use of antihypertensive drugs on prostate cancer (PCa)-specific survival and the initiation of androgen deprivation therapy (ADT).
A. Siltari, T. Murtola, K. Talala, K. Taari, T. Tammela, A. Auvinen   +5 more
semanticscholar   +1 more source

Clinical Applicability of Monitoring Antihypertensive Drug Levels in Blood

HYPERTENSION, 2020
Supplemental Digital Content is available in the text. Dried blood spot (DBS) analysis is a novel analytical method for therapeutic drug monitoring to identify nonadherence to antihypertensive drugs.
L. Peeters, L. Feyz, E. Boersma, J. Daemen, T. van Gelder, B. Koch, J. Versmissen   +6 more
semanticscholar   +1 more source