Low adherence of patients to antihypertensive therapy remains an urgent problem and is recognized as the main cause of insufficient BP control at the population level.
Marina V. Leonova
doaj +1 more source
The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis. [PDF]
BACKGROUND: The purpose of our study was to evaluate the effects of a new reimbursement rule for antihypertensive medication that made thiazides mandatory first-line drugs for newly treated, uncomplicated hypertension. The objective of the new regulation
Atle Fretheim +4 more
doaj +1 more source
According to the World Health Organization (WHO), hypertension affects 22% of the world's population. Hypertension is also the cause of death with 23.7% of the total 1.7 million deaths in Indonesia in 2016. Based on the medical record sheet at H. Hanafie
Tri Wasilah, Rasmala Dewi, Deny Sutrisno
doaj +1 more source
Background: The number of antihypertensive drug classes cannot accurately reflect the total consumption of antihypertensive drugs used to control blood pressure.
Takanobu Utsumi +9 more
doaj +1 more source
Patterns of antihypertensive prescribing, discontinuation and switching among a Hong Kong Chinese population from over one million prescriptions [PDF]
Hypertension is an alarming public health problem among Chinese. The present study evaluated the prescribing patterns, discontinuation and switching profiles of antihypertensive agents and their associated factors in one Hong Kong Chinese population ...
A Fretheim +14 more
core +1 more source
Whey-derived peptides interactions with ACE by molecular docking as a potential predictive tool of natural ACE inhibitors [PDF]
Several milk/whey derived peptides possess high in vitro angiotensin I-converting enzyme (ACE) inhibitory activity. However, in some cases, poor correlation between the in vitro ACE inhibitory activity and the in vivo antihypertensive activity has been ...
Chamata, Yara +2 more
core +1 more source
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H. +6 more
core +1 more source
Efficient and improved synthesis of Telmisartan
An efficient synthesis of the angiotensin II receptor antagonist Telmisartan (1) is presented involving a cross coupling of 4-formylphenylboronic acid 10 with 2-(2-bromophenyl)-4,4-dimethyl-2-oxazoline (11) as the key step (90% yield).
A. Sanjeev Kumar +2 more
doaj +1 more source
Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O. +4 more
core +1 more source
Personalized medicine—a modern approach for the diagnosis and management of hypertension [PDF]
The main goal of treating hypertension is to reduce blood pressure to physiological levels and thereby prevent risk of cardiovascular disease and hypertension-associated target organ damage.
Borghi, Claudio +5 more
core +1 more source

