Results 21 to 30 of about 139,220 (339)

Efficient and improved synthesis of Telmisartan

Beilstein Journal of Organic Chemistry, 2010
An efficient synthesis of the angiotensin II receptor antagonist Telmisartan (1) is presented involving a cross coupling of 4-formylphenylboronic acid 10 with 2-(2-bromophenyl)-4,4-dimethyl-2-oxazoline (11) as the key step (90% yield).
A. Sanjeev Kumar, Samir Ghosh, G. N. Mehta   +2 more
doaj   +1 more source

On the issue of low adherence of patients to antihypertensive therapy: the use of therapeutic drug monitoring of drugs: A review

Consilium Medicum, 2022
Low adherence of patients to antihypertensive therapy remains an urgent problem and is recognized as the main cause of insufficient BP control at the population level.
Marina V. Leonova
doaj   +1 more source

Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]

, 2016
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H., Dominiczak, Anna F., Mccallum, Linsay, Muir, Scott, Padmanabhan, Sandosh, Smith, Daniel J., Touyz, Rhian M.   +6 more
core   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O., Diener, H. C., Glahn, J., Hamann, Gerhard F., Weimar, C.   +4 more
core   +1 more source

Real-World Prescribing Patterns for Hypertensive Children in China from 2018 to 2021: A Cross-Sectional Multicenter Study

Risk Management and Healthcare Policy, 2023
Qin Qian,* Yu-Zhen Wang,* Lian-Di Kan,* Jie Chen, Chen Wang, Gang Han, Liu-Cheng Li, Wei-Jian Lou Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, People’s Republic of China&ast ...
Qian Q, Wang YZ, Kan LD, Chen J, Wang C, Han G, Li LC, Lou WJ   +7 more
doaj  

Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth

Journal of Indian Society of Periodontology, 2019
Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs.
Sameera Gopinath, Vadakkedath Venugopal Harishkumar, Vediyera Chandroth Santhosh, Sreekanth Puthalath   +3 more
doaj   +1 more source

The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis. [PDF]

PLoS Medicine, 2007
BACKGROUND: The purpose of our study was to evaluate the effects of a new reimbursement rule for antihypertensive medication that made thiazides mandatory first-line drugs for newly treated, uncomplicated hypertension. The objective of the new regulation
Atle Fretheim, Kari Håvelsrud, Graeme MacLennan, Doris Tove Kristoffersen, Andrew D Oxman   +4 more
doaj   +1 more source

A comparative study of antihypertensive drugs prediction models for the elderly based on machine learning algorithms

Frontiers in Cardiovascular Medicine, 2022
BackgroundGlobally, blood pressure management strategies were ineffective, and a low percentage of patients receiving hypertension treatment had their blood pressure controlled.
Tiantian Wang, Yongjie Yan, Shoushu Xiang, Juntao Tan, Chen Yang, Wenlong Zhao   +5 more
doaj   +1 more source

Drug interactions of antihypertensive agents

South African Family Practice, 2012
No abstract available.
L.H. Opie
doaj   +1 more source

Comparison of First-Line Dual Combination Treatments in Hypertension: Real-World Evidence from Multinational Heterogeneous Cohorts. [PDF]

, 2020
Background and objectives: 2018 ESC/ESH Hypertension guideline recommends 2-drug combination as initial anti-hypertensive therapy. However, real-world evidence for effectiveness of recommended regimens remains limited.
Cho, Jaehyeong, Hripcsak, George, Jung, Sungjae, Lee, Seongwon, Park, Rae Woong, Park, Sungha, Ryan, Patrick B, Schuemie, Martijn J, Suchard, Marc A, Swerdel, Joel N, You, Seng Chan   +10 more
core   +2 more sources