Results 61 to 70 of about 93,748 (310)

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality

open access: yesHepatology, EarlyView., 2022
Visualisation of the study desgin, main results and key findings. Abstract Background and Aims MAFLD often cooccurs with excessive alcohol consumption, while its prognostic value in this group remains unclear. We aimed to study the mortality risk of MAFLD in relation to excessive alcohol consumption and its potential interactions.
Laurens A. van Kleef   +2 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca   +2 more
wiley   +1 more source

Prescription pattern of antihypertensive drugs: An experience from a secondary care hospital in the United Arab Emirates

open access: yesJournal of Research in Pharmacy Practice, 2019
Objective: The aim of the study was to examine the prescription pattern of antihypertensive drugs used in a secondary care hospital in the United Arab Emirates (UAE).
Maryam Salem Alkaabi   +3 more
doaj   +1 more source

Untargeted Metabolomics Reveals Seasonal and Tissue‐Specific Metabolic Shifts in Holothuria cinerascens

open access: yesChemistry &Biodiversity, EarlyView.
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Cassandra Upton   +3 more
wiley   +1 more source

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel   +9 more
wiley   +1 more source

The Combination of Beta Blockers and Renin-Angiotensin System Blockers Improves Survival in Incident Hemodialysis Patients: A Propensity-Matched Study

open access: yesKidney International Reports, 2017
Although several studies suggest that the prognosis of hypertensive dialysis patients can be improved by using antihypertensive drug therapy, it is unknown whether the prescription of a particular class or combination of antihypertensive drugs is ...
José Luño   +22 more
doaj   +1 more source

The One‐Step Synthesis of Biologically Active Isochromans from Lignin‐Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

open access: yesChemistry – A European Journal, EarlyView.
A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi   +6 more
wiley   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang   +17 more
wiley   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik   +7 more
wiley   +1 more source

Medication Literacy in a Cohort of Chinese Patients Discharged With Essential Hypertension

open access: yesFrontiers in Public Health, 2020
Background: In recent years, research on medication literacy has increased in many countries. Medication literacy in patients with essential hypertension affects the management and prognosis of hypertension.Method: This is a cross-sectional study of 147 ...
Zhuqing Zhong   +8 more
doaj   +1 more source

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