Results 51 to 60 of about 152,056 (303)

紫苏籽油的抗衰老作用及机制探究 Anti-aging effect and mechanisms of perilla seed oil

Zhongguo youzhi
旨在为紫苏籽油的开发利用提供理论依据，以D-半乳糖（500 mg/kg）在小鼠颈背部皮下连续注射4周建立小鼠衰老模型后，将小鼠随机分为模型对照组（生理盐水）、阳性对照组（维生素C 200 mg/kg）和紫苏籽油高（5 mL/kg）、中（2.5 mL/kg）、低（1.25 mL/kg）剂量组，连续灌胃4周，记录小鼠体质量及行为变化，通过转棒法和金属网法检测小鼠的协调运动能力，测定小鼠主要脏器（脑、胸腺、脾脏）指数以及小鼠血清和脑组织匀浆中谷胱甘肽过氧化物酶（GSH-Px）活力和丙二醛（MDA）含量 ...
王荣1,2,3，王娜娜1,2,3，杨宽1,2,3，刘自群1，秦蓓1,2,3 WANG Rong1,2,3，WANG Nana1,2,3， YANG Kuan1,2,3， LIU Ziqun1，QIN Bei1,2,3
doaj   +1 more source

The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]

, 2019
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia, Ceccato, Filippo, Scaroni, Carla   +2 more
core   +1 more source

EFFECT OF ANTIHYPERTENSIVE DRUGS ON QUALITY OF LIFE IN PATIENTS WITH ARTERIAL HYPERTENSION

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study effect of antihypertensive drugs on quality of life (QoL) of patients with stable arterial hypertension (HT).Material and methods. Results of some studies with similar design involving totally 170 patients with HT, aged 57,2±8,8 y.o., were ...
G. F. Andreeva, A. D. Deev, V. M. Gorbunov   +2 more
doaj   +3 more sources

The Use of Antihypertensive and Antiplatelet Drugs on Hospital Stroke Patients [PDF]

, 2016
Medicine is one of the most important part of the healing process, the restoration of health and prevention of disease. This study aims to describe the use of drugs, particularly antihypertensive and antiplatelet drugs in stroke patients hospitalized in ...
Abdullah, A. (Akrom), Budiyono, B. (Budiyono), Putri, A. R. (Anggy)   +2 more
core  

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.

, 2013
BACKGROUND: numerous reports have linked impaired kidney function to a higher risk of cardiovascular events and mortality. There are relatively few data relating to kidney function in the very elderly. METHODS: the Hypertension in the Very Elderly Trial (
Beckett, Nigel, Bulpitt, Christopher, Burch, Lisa, Fagard, Robert, Fletcher, Astrid, Li, Mengying, Narkiewicz, Krzysztof, Nitsch, Dorothea, Peters, Ruth, Poulter, Ruth, Wang, Nan   +10 more
core   +1 more source

Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study [PDF]

, 2013
Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity.
A Weeke, AJ Ferrari, AJ Mitchell, B Felker, B Ya-Mei, Bruce Guthrie, C Astrup, C Crump, CW Colton, Daniel J Smith, Daniel Martin, DJ Smith, E Koranyi, EH Høyer, F Angst, FG Joseph, Gary McLean, J Johnson, J Langan, JA Mackell, Julie Langan, K Barnett, LM Koran, M De Hert, M De Hert, M De Hert, M Tohen, MJ Fleury, MT Tsuang, N Myles, O Bratfos, P Vestergaard, PA Kurdyak, R Sharma, RM Weinryb, SH Han, Stewart W Mercer, T Callréus, TM Laursen, TM Laursen, U Osby, U Petterson, VMR Carstairs   +42 more
core   +3 more sources

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source