Results 141 to 150 of about 2,381,911 (194)

Different blood lipid profiles and their role in cardiometabolic disease progression: A comparative study between an East Asian and European Large Prospective Cohorts

open access: yesVIEW, EarlyView.
In this study, we analyzed data from the Kailuan study in China (N = 95,711) and the UK Biobank (N = 388,317), comprising adults free of CMDs at baseline. The results demonstrated distinct, population‐specific patterns regarding how blood lipids influence the transition from a healthy state to incident CMDs and subsequently to CMM.
Lili Huang   +16 more
wiley   +1 more source

The evolution of antihypertensive therapy

open access: yes
The goal of antihypertensive therapy has changed dramatically over the past 40 years. What was once a treatment for a life-threatening disease has gradually evolved to become just one of the many ways of modifying a symptomless risk factor.
Kawachi, Ichiro, Wilson, Nicholas
core  

Long‐Term Outcomes of Omniflow II and BioIntegral Xenografts for Open Aortic Reconstruction in Predominantly Infected Settings: A Multicenter Cohort Study

open access: yesWorld Journal of Surgery, EarlyView.
Evidence surrounding conduit selection for open in situ aortic reconstruction remains limited, particularly for xenograft use in infected settings. We evaluated long‐term outcomes after open aortic and aorto‐iliac reconstruction using BioIntegral No‐React bovine grafts and Omniflow II biosynthetic grafts in patients unsuitable for autologous vein ...
Tijmen W. Kraai   +6 more
wiley   +1 more source

Treatment Patterns and Pathways of Systemic Drug Therapy in Patients With Plaque, Erythrodermic, and Generalized Pustular Psoriasis: A Retrospective Cohort Study in Japan

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada   +9 more
wiley   +1 more source

First Trimester Screening for Preterm Preeclampsia in the United Kingdom: A Cost‐Effectiveness Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the cost‐effectiveness of the Fetal Medicine Foundation (FMF) strategy, compared with the National Institute for Health and Care Excellence (NICE) strategy, for first‐trimester screening for preterm preeclampsia (PE) in the United Kingdom (UK). Design Cost‐effectiveness analysis.
Mohammad A. Ani   +4 more
wiley   +1 more source

Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time‐averaged cumulative systolic blood pressure (TACsBP‐inD) as a new metric

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 525-534, June 2025.
Abstract Background Blood pressure is a crucial risk factor for hemodialysis patients, but the specific impact of weather factors, particularly barometric pressure, on blood pressure remains unclear. This study aims to examine the relationship between barometric pressure and blood pressure in hemodialysis patients. Methods We conducted a single‐center,
Kosaku Iwatsubo   +2 more
wiley   +1 more source

Current Pharmacology of Antihypertensive Agents

open access: yes
The thesis addresses how current antihypertensive drugs work by studying their mechanism of action, effectiveness and safety profile alongside non-drug treatments for hypertension which include dietary and lifestyle modifications.
Shafei , Maryam
core  

Cardiometabolic Treatment Gap in Routine Psychiatric Care: A Cross‐Sectional Study of 1553 Patients

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background People with severe mental illness (SMI) have elevated cardiometabolic morbidity and mortality, with similar concerns increasingly reported in other psychiatric conditions including anxiety disorders and ADHD. Somatic conditions are often underdiagnosed and pharmacologically undermanaged in this population.
Vincent Achour   +4 more
wiley   +1 more source

Prognostic significance of prior alcohol use disorder in patients with presumed metabolic dysfunction‐associated steatotic liver disease: A large multi‐center cohort study

open access: yesAddiction, EarlyView.
Abstract Background and aims Alcohol use disorder (AUD) follows a chronic, relapsing course but is often overlooked when alcohol consumption is minimal at the time of evaluation. We aimed to assess the prognostic impact of a prior AUD diagnosis on liver‐related outcomes in patients with presumed metabolic dysfunction‐associated steatotic liver disease (
Butros Fakhoury   +6 more
wiley   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

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