Results 91 to 100 of about 12,043,843 (293)
Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases [PDF]
, 2021 Jonathan Bogaerts +7 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang +17 more
wiley +1 more source
Prognostic value of blood pressure in the acute period of hemispheric ischemic stroke
Кардиоваскулярная терапия и профилактикаAim. To study changes in blood pressure (BP) in patients with acute hemispheric ischemic stroke (AIS), to correlate BP in patients with AIS with BP in patients with chronic brain ischemia, and to study the association of various BP indices with stroke ...
E. I. Gusev +4 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik +7 more
wiley +1 more source
Prevalence of hypertension in the urban population of Catanduva, in the State of São Paulo, Brazil
Arquivos Brasileiros de Cardiologia, 2001 OBJECTIVE: To study the prevalence of systemic hypertension and its control in the population of Catanduva, in the state of São Paulo, Brazil. METHODS: We carried out a randomized cross-sectional population-based study of the urban population of ...
Olavo de Carvalho Freitas +7 more
doaj +1 more source
Cost-effectiveness analysis of initial treatment with single-pill combination antihypertensive medications [PDF]
, 2023 Alexis Bryan +8 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum +10 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Hydralazine is a vasodilator typically used in the treatment of resistant hypertension and heart failure. N‐acetyltransferase 2 (NAT2) catalyzes the metabolism of hydralazine into inactive metabolites. NAT2 poor metabolizers (historically referred to as “slow acetylators”) are predicted to have increased plasma hydralazine concentrations compared with ...
Michael T. Eadon +18 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source