Results 221 to 230 of about 67,136 (328)

Network medicine and systems pharmacology approaches to predicting adverse drug effects

British Journal of Pharmacology, EarlyView.
Identifying and understanding the relationships between drug intake and adverse effects that can occur due to inadvertent molecular interactions between drugs and targets is a difficult task, especially considering the numerous variables that can influence the onset of such events.
Alessio Funari, Giulia Fiscon, Paola Paci   +2 more
wiley   +1 more source

Association between cardiovascular, psychotropic and anti-inflammatory/analgesic drug use and vascular dysfunction in individuals with long COVID. BioICOPER study. [PDF]

Front Cardiovasc Med
Arroyo-Romero S, Gómez-Sánchez L, Suárez-Moreno N, Navarro-Cáceres A, Domínguez-Martín A, Lugones-Sánchez C, González-Sánchez S, Sánchez-Moreno A, Rodríguez-Sánchez E, García-Ortiz L, Navarro-Matias E, Gómez-Marcos MA.   +11 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Cf-PWV but not cr-PWV or cd-PWV is associated with cardiovascular mortality in patients with chronic kidney disease. [PDF]

BMC Nephrol
Wang Y, Liu HX, Xiong JR, Sui Z, Wang M, Zuo L, Wang M.   +6 more
europepmc   +1 more source

Corrigendum: Prescription pattern and effectiveness of antihypertensive drugs in patients with aortic dissection who underwent surgery [PDF]

Kuang‐Ming Liao, Chuan-Wei Shen, Yunhui Huang, Chun-Hui Lu, Hsuan-Lin Lai, Chung‐Yu Chen   +5 more
openalex   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

British Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu, Yanyan Zhang, Meiling Shan, Jiaqi Cao, Zihan Fan, Zhaoxia Xu, Xiaozhen Ding, Xiaodong Liu, Lijun Shi   +8 more
wiley   +1 more source

The anti-aging potential of antihypertensive peptides of Pariset, a dataset of algal peptides [PDF]

Isaac Karimi, Parisa Olfati, Layth Jasim Mohammed, Jawad Kadhim Tarrad, Ahmed M. Amshawee, Maryam A. Hussain, Helgi B. Schiöth   +6 more
openalex   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Differences in cardiovascular disease incidence according to changes in obesity status in young diabetic patients. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Song DK, Sung YA, Hong YS, Kim MH, Lee H.   +4 more
europepmc   +1 more source

TNF Centered Multitarget Antihypertensive Mechanisms of Andrographis paniculata Compounds Revealed by Network Pharmacology, Molecular Docking, Molecular Dynamics

Sefren Geiner Tumilaar, Maulida Mazaya
openalex   +1 more source