S1‐Guideline for diagnosis and therapy of necrobiosis lipoidica
Summary Necrobiosis lipoidica (NL) is a rare granulomatous skin disease of unknown etiology that occurs frequently in association with diabetes mellitus and other comorbidities. The predilection site is the lower leg, particularly the pretibial areas. The exact pathogenesis remains unclear.
Cornelia Erfurt‐Berge +6 more
wiley +1 more source
Humanization of Drug Metabolism in the <i>Plasmodium berghei</i> Mouse Model for Antimalarial Drug Discovery. [PDF]
MacLeod AK +15 more
europepmc +1 more source
Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley +1 more source
Home Treatment of Childhood Illnesses Prior to Seeking Formal Care: A Cross-Sectional Study at Different Health Care Levels in Ghana. [PDF]
Rautman LH +10 more
europepmc +1 more source
Genomic Insights Into Host Shifts Between Plasmodium vivax and Plasmodium simium in Latin America
ABSTRACT Malaria in Latin America is largely caused by Plasmodium vivax, but the closely related monkey parasite Plasmodium simium has recently been observed in humans, thus raising new public health concerns. By screening 719 monkey samples from five Latin America countries, we identified 23 Plasmodium‐positives.
Margaux J. M. Lefebvre +16 more
wiley +1 more source
The urgent need for African research collaboration on medicine quality. [PDF]
Zeng F +4 more
europepmc +1 more source
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Dengue diagnosis and impact on clinical management: A literature review. [PDF]
Robert S +5 more
europepmc +1 more source
This study provides the first cost analysis of integrating a WASH kit into outpatient SAM treatment in Senegal, highlighting key cost drivers and potential efficiencies for scale‐up. Findings offer practical insights for planning and budgeting integrated WASH‐nutrition interventions in similar settings.
Bibata Wassonguema +11 more
wiley +1 more source
Asymptomatic malaria: a hidden reservoir for the transmission and circulation of artemisinin partial-resistant <i>Plasmodium falciparum</i> in Tanzania. [PDF]
Mazigo E +20 more
europepmc +1 more source

