Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood. [PDF]
Saito M +13 more
europepmc +1 more source
Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö +8 more
wiley +1 more source
Telitacicept versus belimumab for the treatment of systemic lupus erythematosus: a network meta-analysis and cost-effectiveness analysis. [PDF]
Deng L +6 more
europepmc +1 more source
This study provides the first cost analysis of integrating a WASH kit into outpatient SAM treatment in Senegal, highlighting key cost drivers and potential efficiencies for scale‐up. Findings offer practical insights for planning and budgeting integrated WASH‐nutrition interventions in similar settings.
Bibata Wassonguema +11 more
wiley +1 more source
Development of substituted 2-(4-(sulfonyl)piperazin-1-yl)quinazoline molecular hybrids as a new class of antimalarials. [PDF]
Madhav H +9 more
europepmc +1 more source
Aims Resistance to the artemisinins and the artemisinin‐based combination therapy (ACT) partner drugs has developed in Southeast Asia, and artemisinin resistance has also emerged in eastern Africa. Triple ACTs (triple artemisinin‐based combination therapies, TACT), consisting of two partner drugs with different mechanisms of action and similar ...
Junjie Ding +24 more
wiley +1 more source
Accessibility to antimalarials in Spanish hospitals: analysis of a national survey. [PDF]
Bretones-Pedrinaci JI +4 more
europepmc +1 more source
Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel +9 more
wiley +1 more source
Artemether-lumefantrine versus pyronaridine-artesunate for the treatment of malaria in patients with mild to moderate COVID-19 in Kenya and Burkina Faso: a randomised open-label trial (MALCOV). [PDF]
Tangara B +30 more
europepmc +1 more source

