Results 171 to 180 of about 63,797 (281)

Liquid-Phase Peptide Synthesis of Tropolone-Peptide Hybrid Antimalarials. [PDF]

Org Lett
Sennari G, Nakajima A, Nakahara H, Saito R, Ishiyama A, Hokari R, Iwatsuki M, Hirose T, Sunazuka T.   +8 more
europepmc   +1 more source

Graph‐Theoretical Approach for Predicting Physicochemical Properties of Stiff‐Person Syndrome Drugs

ChemistryOpen, Volume 15, Issue 6, June 2026.
Graph‐theoretical descriptors derived from M‐polynomials are integrated with quantitative structure–property relationship modeling and machine learning to uncover structure–property relationships of drugs used in stiff‐person syndrome. Strong correlations between degree‐based topological indices and key physicochemical properties are revealed ...
Jabbar Ali, Yasir Ali, Maher Ali Malik, Yilun Shang   +3 more
wiley   +1 more source

Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries. [PDF]

BMJ Open
McElwee F, Farlow A, Guerin PJ.
europepmc   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

Acute generalized exanthematous pustulosis sine pustules: A case report. [PDF]

JAAD Case Rep
Ali A, O'Brien MA, Hsu S.
europepmc   +1 more source

Public Health Achievements in Rwanda: A 21st Century Transformation

Public Health Challenges, Volume 5, Issue 2, June 2026.
This narrative review examines Rwanda's post‐2000 public health transformation using the WHO health system building blocks. It shows how strategic governance, universal health coverage via mutuelle de santé, community health workers, and digital health tools have driven substantial gains in maternal/child health, infectious disease control, and ...
Niyibizi Julius, Mugisha John, Nizeyimana Emmanuel   +2 more
wiley   +1 more source

Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria among children 6-59 months in three sentinel sites of Sierra Leone, 2021-2022. [PDF]

Malar J
Cavros I, Abanyie F, Kamara ARY, Chalobah F, Fofana N, Ahmed J, Larbi K, Kennedy C, Horton B, Bajic M, Richardson M, Matlock B, McCaffery J, Kanu S, Schnabel D, Labor TSA, Cash S, Plucinski M, Komeh JP, Sillah-Kanu M.   +19 more
europepmc   +1 more source

Pharmaceutical Wastage in Public Health Facilities of Ethiopia: Determinants, Consequences, and Solutions

Public Health Challenges, Volume 5, Issue 2, June 2026.
A mixed‐methods study of 17 Ethiopian public health facilities found pharmaceutical wastage of ETB 12.2 million (4.0%), mainly from expiration (98%). Key drivers included weak accountability, near‐expiry deliveries, and poor forecasting. Strengthening electronic inventory systems and redistribution mechanisms can substantially reduce losses and improve
Ewunetie Mekashaw Bayked, Adam Tesfaw Debeb, Getachew Moges, Husien Nurahmed Toleha, Teklehaimanot Fentie Wendie, Minimize Hassen   +5 more
wiley   +1 more source

Development of substituted 2-(4-(sulfonyl)piperazin-1-yl)quinazoline molecular hybrids as a new class of antimalarials. [PDF]

RSC Adv
Madhav H, Panda A, Datta D, Shaheen K, Rahman A, Khan AT, Bhattacharjee S, Kumar D, Malhotra P, Hoda N.   +9 more
europepmc   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, Volume 26, Issue 6, June 2026.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source