Results 151 to 160 of about 28,999 (273)
The splicing of phenoxypyridine moieties to isoquinolin‐3‐carboxylic acid enhanced its biological activity against plant pathogenic fungi. Among target compounds, compound X6 demonstrated significant antifungal activity against Botrytis cinerea in vitro and in vivo assays, Molecular docking, molecular dynamics simulations, as well as SDH enzyme assay ...
Jiayao Zhang +7 more
wiley +1 more source
Endophytic Fungi Natural Factories of Novel Bioactive Compounds
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev +18 more
wiley +1 more source
ABSTRACT Antimalarial cardiotoxicity may mimic lupus myocarditis in systemic lupus erythematosus. We report a 53‐year‐old woman with chronic antimalarial exposure, myocardial injury, biventricular dysfunction, electrical abnormalities, low lupus activity, and no myocardial edema.
Diego Armando Pérez Covo +9 more
wiley +1 more source
ABSTRACT Malaria‐associated secondary HLH, though rare, is often overlooked. Clinicians should maintain a high‐index of suspicion in travelers returning from malaria‐endemic regions who develop severe to rapidly worsening inflammatory illness, as early recognition is critical for survival.
Indresh Yadav +4 more
wiley +1 more source
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley +1 more source
Longitudinal melanonychia and skin hyperpigmentation associated with hydroxychloroquine therapy
Jose W. Ricardo, MD +3 more
doaj +1 more source
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán +5 more
wiley +1 more source
Acute acalculous cholecystitis and blackwater fever with acute kidney injury in children with malaria: case series and literature review. [PDF]
Cugliari M +4 more
europepmc +1 more source
Lactoferrin and Nanotechnology: New Insights Into Glioblastoma Therapy
Current glioblastoma multiforme (GBM) management primarily relies on surgery, chemotherapy, and radiotherapy; however, therapeutic efficacy remains limited due to tumor invasiveness and restricted drug penetration across the blood–brain barrier. Lactoferrin (LF), an iron‐binding glycoprotein with receptor‐mediated transport capability, has emerged as a
Atena Abed, Javad Amini Mahabadi
wiley +1 more source
Nearly one in five essential medicines fail quality standards in Africa: A systematic review and meta-analysis of MNCH medicines and antimalarials. [PDF]
Rusatira JC +10 more
europepmc +1 more source

