Results 11 to 20 of about 1,501,058 (128)
Efficacy of Different Combination Therapies for Mania in Bipolar Disorder: A Systematic Review and Meta-Analysis. [PDF]
Brain BehavABSTRACT Objective To systematically evaluate the efficacy and safety of different combination therapies in the treatment of mania in bipolar disorder, and to provide evidence‐based support for individualized clinical treatment. Methods PubMed, Web of Science, Cochrane Library, CNKI, VIP, and Wanfang databases were systematically searched from ...
Yao P, Ni P, Yin L.
europepmc +2 more sources
Ontology acquisition and exchange of evolutionary product-brokering agents [PDF]
, 2004 Agent-based electronic commerce (e-commerce) has been booming with the development of the Internet and agent technologies. However, little effort has been devoted to exploring the learning and evolving capabilities of software agents.
Guan, SU, Zhu, F
core +6 more sources
The role of NMDA receptors in bipolar disorder: A systematic review
Bipolar Disorders, Volume 25, Issue 8, Page 624-636, December 2023., 2023 Abstract Objectives Glutamatergic transmission and N‐methyl‐D‐aspartate receptors (NMDARs) have been implicated in the pathophysiology schizophrenic spectrum and major depressive disorders. Less is known about the role of NMDARs in bipolar disorder (BD).
Francesco Weiss +6 more
wiley +1 more source
Bipolar Disorders, Volume 25, Issue 7, Page 583-591, November 2023., 2023 Abstract Introduction Antidepressants are commonly used “off‐label” for bipolar depression, despite concerns over the risk of potential treatment‐emergent mania (or “manic switch”). Treatment‐emergent mania is difficult to study with adequate power in clinical trials as it requires a large group of participants and long follow‐up.
Oskar Hougaard Jefsen +2 more
wiley +1 more source
Differential treatment of bipolar disorder with old and new antiepileptic drugs [PDF]
, 1998 Although lithium remains the preferred medication for bipolar disorders, new investigations suggest that only 60 to 80% of patients have a good response with a classical presentation.
Normann, C. +7 more
core +1 more source
Effects of memantine on mania‐like phenotypes exhibited by Drosophila Shaker mutants
CNS Neuroscience &Therapeutics, Volume 29, Issue 7, Page 1750-1761, July 2023., 2023 Amelioration of functional and metabolic parameters in Drosophila mutant upon memantine treatment. Abstract Introduction Increased glutamate levels and electrolytic fluctuations have been observed in acutely manic patients. Despite some efficacy of the non‐competitive NMDA receptor antagonist memantine (Mem), such as antidepressant‐like and mood ...
Ignazia Mocci +11 more
wiley +1 more source
Bipolar Disorders, Volume 25, Issue 3, Page 221-232, May 2023., 2023 Abstract Background There remain few efficacious treatments for bipolar depression, which dominates the course of bipolar disorder (BD). Despite multiple studies reporting associations between depression and cerebral blood flow (CBF), little is known regarding CBF as a treatment target, or predictor and/or indicator of treatment response, in BD ...
William S. H. Kim +16 more
wiley +1 more source
Case Reports in Psychiatry, Volume 2023, Issue 1, 2023., 2023 First‐line treatments for schizophrenia and schizoaffective disorder include antipsychotics and mood stabilizers, but their use may at times be limited due to severe adverse events. This case describes a 41‐year‐old male with a history of schizoaffective disorder and polysubstance use who was admitted to an inpatient psychiatry unit for acute manic and
David S. Im +3 more
wiley +1 more source
LITHIUM, CARBAMAZEPINE AND VALPROATE IN ACUTE MANIA
Psychiatry and Clinical Psychopharmacology, 2021 Objective: Mood stabilizers are frequently used in the management of acute mania. Lithium has been used for this indication since Cade first described its effectiveness in psychotic excitation in 1949.
M. Erkan Özcan, A. Vahap Boztepe
doaj
HOW ASSESS DRUGS IN THE TREATMENT OF ACUTE BIPOLAR MANIA ?
Frontiers in Pharmacology, 2013 Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes.
Michel eBourin, Florence eThibaut
doaj +1 more source