Results 81 to 90 of about 1,476 (103)
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A population‐based study of the comparative effectiveness of second‐generation antipsychotics vs older antimanic agents in bipolar disorder

Bipolar Disorders, 2016
ObjectivesNumerous antimanic treatments have been introduced over the past two decades, particularly second‐generation antipsychotics (SGAs). However, it is not clear whether such newer agents provide any advantage over older treatments.MethodsA historical cohort design investigated the nationwide population of outpatients with bipolar disorder treated
Mark S, Bauer   +4 more
exaly   +3 more sources

Antimanic and mood‐stabilizing effect of memantine as an augmenting agent in treatment‐resistant bipolar disorder

Bipolar Disorders, 2010
Memantine is a selective, uncompetitive N-methyl- D-aspartate (NMDA) receptor antagonist, currently used in the treatment of Alzheimers disease. Many clinical trials have demonstrated its tolerability and safety. We have suggested that antidepressants induce mania and rapid cycling by sensitizing dopamine D2 receptors and demonstrated that the ...
Athanasios Koukopoulos   +5 more
openaire   +3 more sources

Antimanic agents : a pharmacoepidemiologic study

Neurologia Croatica. Supplement, 1997
In the treatment of bipolar affective disorders many agents have been used. An epidemiologic descriptive analysis of the drug treatment in patients with bipolar affective disorders often includes lithium, carbamazepine or valproate. These agents have shown to be effective in the acute or maintenance treatment of mania in numerous clinical trials and ...
Makarić, Gordan   +3 more
openaire   +2 more sources

Structurally Dissimilar Antimanic Agents Modulate Synaptic Plasticity by Regulating AMPA Glutamate Receptor Subunit GluR1 Synaptic Expression

Annals of the New York Academy of Sciences, 2003
Abstract: A growing body of data from clinical and preclinical studies suggests that the glutamatergic system may represent a novel therapeutic target for severe recurrent mood disorders. Since synapse‐specific glutamate receptor expression/localization is known to play critical roles in synaptic plasticity, we investigated the effects of mood ...
Jing, Du   +5 more
openaire   +2 more sources

Health-economic implications of the onset of action of antimanic agents.

The Journal of clinical psychiatry, 1997
Three medications, lithium, valproate, and carbamazepine, have been shown to be effective in the treatment of acute mania in randomized, controlled clinical trials. Additional research over the past decade has provided data regarding potential differences between these medications according to their time course of onset and clinical predictors of ...
P E, Keck, S L, McElroy, J A, Bennett
openaire   +1 more source

The relationship between antimanic agent for treatment of classic or dysphoric mania and length of hospital stay.

The Journal of clinical psychiatry, 1996
This retrospective study was conducted to evaluate the relationship between the mood-stabilizing agents lithium, carbamazepine, and divalproex sodium and time course of drug response as measured by length of hospital stay.Seventy-eight patients were evaluated.
M A, Frye   +4 more
openaire   +1 more source

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