Results 221 to 230 of about 90,280 (287)

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Cheap, Fast, Safe, Sustainable, and Positively Irresistible: The Future of Cationic Amphiphilic Disinfectant Development. [PDF]

J Med Chem
Hedges MR, Minbiole KPC, Selinsky BS, Wuest WM.   +3 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Exploiting peptide chirality and transport to dissect the complex mechanism of action of host peptides on bacteria. [PDF]

PLoS Genet
Sankari S, Arnold MFF, Babu VMP, Deutsch M, Walker GC.   +4 more
europepmc   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

Molecular Microbiology, EarlyView.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz, Lina Brodskaia, Christiane Fritz, Stefanie Hebecker, Maike K. Tauchert, Jennifer Breisch, Dieter Jahn, Franz Narberhaus, Jürgen Moser, Meriyem Aktas   +9 more
wiley   +1 more source

Host defense peptides in malaria infection: their contributions, significance and constraints. [PDF]

Malar J
Alfaki DA, Elbasheir MM.
europepmc   +1 more source

Effector‐Mediated Spatial Reprogramming of Glycolate Oxidase Subverts Peroxisomal and Membrane‐Associated ROS Defences

Plant Biotechnology Journal, EarlyView.
ABSTRACT Oomycete pathogens secrete hundreds of RXLR effectors into plant cells to modulate host immunity by targeting diverse plant proteins. Here, we report that the Peronophythora litchii RXLR effector PlAvh133 acts as a virulence factor and targets the litchi glycolate oxidase (GLO) LcGLO1, a key enzyme in photorespiration, thereby suppressing ...
Junjian Situ, Zijing Zhang, Yi Shao, Jiaying Feng, Feiteng Zhong, Muran Xiong, Wen Li, Peng Li, Xiaofan Zhou, Guibing Hu, Jietang Zhao, Minhui Li, Pinggen Xi, Xinxiang Peng, Zide Jiang, Guanghui Kong   +15 more
wiley   +1 more source

Plant Peptides on the Rise: From Historical Insight to Future Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant peptides constitute a rapidly expanding class of signalling molecules essential to plant physiology, mediating key processes such as development, stress adaptation, and immune responses. This review traces the history of plant peptide research, from the seminal discovery of systemin to the recent identification of non‐canonical peptides (
Shunxi Wang, Jinghua Zhang, Minghui Chen, Bokai Zhang, Huina Zhao, Liuji Wu   +5 more
wiley   +1 more source