The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents.
Ali Adem Bahar, Dacheng Ren
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Analysis and Prediction of some Histone-derived Antimicrobial Peptides from Toads Duttaphrynus melanostictus and Phyrinoidis asper [PDF]
Antimicrobial peptides in skin secretions of toads is a promising methods to combat a wide spectrum of bacteria. Histone H2A is a type of DNA-binding protein that acts as a precursor for several antimicrobial peptides. In toads (family Bufonidae) buforin
Muhammad Dailami +2 more
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Design and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an amphipathic α-helical head and an aromatic tail.
Ziyi Tang +13 more
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Targeting Multidrug Resistance With Antimicrobial Peptide-Decorated Nanoparticles and Polymers
As a category of small peptides frequently found in nature, antimicrobial peptides (AMPs) constitute a major part of the innate immune system of various organisms. Antimicrobial peptides feature various inhibitory effects against fungi, bacteria, viruses,
Solmaz Maleki Dizaj +6 more
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Application of Artificial Intelligence Algorithms in the Field of Antimicrobial Peptide Prediction [PDF]
Antimicrobial peptides, as small molecular peptides with extensive antibacterial activity, have shown great potential in food preservation and other fields because of their unique antibacterial mechanism.
QIAN Yuchen, NIE Ting, HUA Yanming, XU Shiying, GUO Sheng, ZHANG Xin, LUO Xiaohu, LIU Yanan
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Legume Plant Peptides as Sources of Novel Antimicrobial Molecules Against Human Pathogens
Antimicrobial peptides are prominent components of the plant immune system acting against a wide variety of pathogens. Legume plants from the inverted repeat lacking clade (IRLC) have evolved a unique gene family encoding nodule-specific cysteine-rich ...
Rui M. Lima +9 more
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Evidence Supporting an Antimicrobial Origin of Targeting Peptides to Endosymbiotic Organelles
Mitochondria and chloroplasts emerged from primary endosymbiosis. Most proteins of the endosymbiont were subsequently expressed in the nucleo-cytosol of the host and organelle-targeted via the acquisition of N-terminal presequences, whose evolutionary ...
Clotilde Garrido +4 more
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Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with ...
Bruhn Oliver +3 more
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The increasing antimicrobial-resistant prevalence has become a severe health problem. It has led to the invention of a new antimicrobial agent such as antimicrobial peptides.
Rima Erviana +7 more
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Recent advances in the field of antimicrobial peptides in inflammatory diseases
Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
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