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De novo peptides as potential antimicrobial agents
The phenomenon of antimicrobial resistance threatens our ability to treat common infections. The clinical pipeline for new antimicrobials is pretty much dry and hence, there is a need for the development of new antimicrobial agents with low toxicities to
Margaret Amerley Amarh +2 more
doaj +1 more source
Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C. +3 more
core +1 more source
Plant antimicrobial peptides [PDF]
Plant antimicrobial peptides (AMPs) are a component of barrier defense system of plants. They have been isolated from roots, seeds, flowers, stems, and leaves of a wide variety of species and have activities towards phytopathogens, as well as against bacteria pathogenic to humans.
Nawrot, Robert +5 more
openaire +2 more sources
Modified CLEC3A-Derived Antimicrobial Peptides Lead to Enhanced Antimicrobial Activity against Drug-Resistant Bacteria [PDF]
Antimicrobial peptides (AMPs) represent a promising alternative to conventional antibiotics. Sequence changes can significantly improve the therapeutic properties of antimicrobial peptides.
Dzemal Elezagic +17 more
core +1 more source
Human Chemokines as Antimicrobial Peptides with Direct Parasiticidal Effect on Leishmania mexicana In Vitro [PDF]
Chemokines and chemokine receptor-mediated effects are important mediators of the immunological response and cure in human leishmaniasis. However, in addition to their signalling properties for leukocytes, many chemokines have also been shown to act ...
Paul Bates (134046) +18 more
core +1 more source
Mechanisms of Antimicrobial Peptides from Bagasse against Human Pathogenic Bacteria
Nonedible agricultural wastes (agricultural wastes, agro-industrial wastes, and fishery wastes) were chosen as potential sources of antimicrobial peptides and evaluated for antibacterial efficiency against human pathogens.
Narumon Phaonakrob +2 more
core +1 more source
Worms’ Antimicrobial Peptides [PDF]
Antimicrobial peptides (AMPs) are natural antibiotics produced by all living organisms. In metazoans, they act as host defense factors by eliminating microbial pathogens. But they also help to select the colonizing bacterial symbionts while coping with specific environmental challenges.
Renato, Bruno +12 more
openaire +6 more sources
Antibiotics are regarded as a miracle in the medical field as it prevents disease caused by pathogenic bacteria. Since the discovery of penicillin, antibiotics have become the foundation for modern medical discoveries.
Noor Aniza Harun +7 more
core +1 more source
Antimicrobial peptides (AMPs) are low-molecular-weight defense polypeptides, produced in all living organisms either constitutively or upon perception of signals from pathogenic microorganisms. They are important components of the immune system in both animals and plants. AMPs differ in structure and mode of action. Most of them belong to cysteine-rich
T. I. Odintsova +7 more
openaire +2 more sources
Peptide Antimicrobial Agents [PDF]
SUMMARYAntimicrobial host defense peptides are produced by all complex organisms as well as some microbes and have diverse and complex antimicrobial activities. Collectively these peptides demonstrate a broad range of antiviral and antibacterial activities and modes of action, and it is important to distinguish between direct microbicidal and indirect ...
Håvard, Jenssen +2 more
openaire +2 more sources

