Results 31 to 40 of about 126,899 (260)
Heliyon, 2019 Peptides are secreted by different cell types and are trendy therapeutic agents that have attracted attention for the treatment of several diseases such as infections.
Reza Esfandiyari +5 more
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Upsala Journal of Medical Sciences, 2014 With increasing antibiotics resistance, there is an urgent need for novel infection therapeutics. Since antimicrobial peptides provide opportunities for this, identification and optimization of such peptides have attracted much interest during recent years.
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AntibioticsAntimicrobial peptides (AMPs) are antibiotic candidates; however, their instability and protease susceptibility limit clinical applications. In this study, the polylactic acid–glycolic acid (PLGA)–polyvinyl alcohol (PVA) drug delivery system was screened
Xuanxuan Ma +6 more
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Peptide Stapling Applied to Antimicrobial Peptides
Antibiotics, 2023 Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço +4 more
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Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
Veterinary Research, 2011 Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with ...
Bruhn Oliver +3 more
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Evidence Supporting an Antimicrobial Origin of Targeting Peptides to Endosymbiotic Organelles
Cells, 2020 Mitochondria and chloroplasts emerged from primary endosymbiosis. Most proteins of the endosymbiont were subsequently expressed in the nucleo-cytosol of the host and organelle-targeted via the acquisition of N-terminal presequences, whose evolutionary ...
Clotilde Garrido +4 more
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Molecules, 2021 The increasing antimicrobial-resistant prevalence has become a severe health problem. It has led to the invention of a new antimicrobial agent such as antimicrobial peptides.
Rima Erviana +7 more
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Antimicrobial Peptides and Colitis [PDF]
Current Pharmaceutical Design, 2012 Antimicrobial peptides (AMPs) are important components of innate immunity. They are often expressed in response to colonic inflammation and infection. Over the last several years, the roles of several antimicrobial peptides have been explored. Gene expression of many AMPs (beta defensin HBD2-4 and cathelicidin) is induced in response to invasion of gut
Samantha, Ho +2 more
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Antimicrobial dendrimeric peptides [PDF]
European Journal of Biochemistry, 2002 Dendrimeric peptides selective for microbial surfaces have been developed to achieve broad antimicrobial activity and low hemolytic activity to human erythrocytes. The dendrimeric core is an asymmetric lysine branching tethered with two to eight copies of a tetrapeptide (R4) or an octapeptide (R8).
James P, Tam, Yi-An, Lu, Jin-Long, Yang
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Recent advances in the field of antimicrobial peptides in inflammatory diseases
Advanced Biomedical Research, 2013 Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
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