Results 51 to 60 of about 151,205 (306)

Antimicrobial dendrimeric peptides [PDF]

European Journal of Biochemistry, 2002
Dendrimeric peptides selective for microbial surfaces have been developed to achieve broad antimicrobial activity and low hemolytic activity to human erythrocytes. The dendrimeric core is an asymmetric lysine branching tethered with two to eight copies of a tetrapeptide (R4) or an octapeptide (R8).
James P, Tam, Yi-An, Lu, Jin-Long, Yang
openaire   +2 more sources

Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS

Frontiers in Pharmacology, 2021
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimicrobial activity. Here, two proline-rich peptides (consP1: VRKPPYLPRPRPRPL-CONH2 and
Kai Hilpert, Jurnorain Gani, Christoph Rumancev, Nathan Simpson, Paula Matilde Lopez-Perez, Vasil M. Garamus, Andreas Robert von Gundlach, Petar Markov, Marco Scocchi, Ralf Mikut, Axel Rosenhahn   +10 more
doaj   +1 more source

Self-assembly antimicrobial peptide for treatment of multidrug-resistant bacterial infection

Journal of Nanobiotechnology
The wide-spreading of multidrug resistance poses a significant threat to human and animal health. Although antimicrobial peptides (AMPs) show great potential application, their instability has severely limited their clinical application.
Xuanxuan Ma, Na Yang, Ruoyu Mao, Ya Hao, Yuanyuan Li, Ying Guo, Da Teng, Yinhua Huang, Jianhua Wang   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antimicrobial Peptides in Cutaneous Wound Healing

, 2016
Injury that breached the physical skin barrier increases the likelihood of infection. The wound healing process is divided into hemostasis, inflammation, proliferation, and tissue remodeling. Antimicrobial peptides play a major role for the antimicrobial
Sørensen, Ole E,, Lund University.
core   +1 more source

Identification of New Antimicrobial Peptides from Mediterranean Medical Plant Charybdis pancration (Steinh.) Speta

, 2020
The present work was designed to identify and characterize novel antimicrobial peptides (AMPs) from Charybdis pancration (Steinh.) Speta, previously named Urginea maritima, is a Mediterranean plant, well-known for its biological properties in traditional
Antonella Di Francesco, Vincenzo Cunsolo, Luigi Inguglia, Vincenzo Arizza, Giampaolo Barone, Rosaria Saletti, Domenico Schillaci, Maria Vitale, Maria Grazia Cusimano, Marco Chiaramonte, Fabrizio Lo Celso, Rosario Schicchi   +11 more
core   +1 more source

Comparative Evaluation of Existing and Rationally Designed Novel Antimicrobial Peptides for Treatment of Skin and Soft Tissue Infections

, 2023
Skin and soft tissue infections (SSTIs) and acne are among the most common skin conditions in primary care. SSTIs caused by ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas ...
Marta Rubina, Anna Ramata-Stunda, Martins Boroduskis, Gints Kalnins, Uldis Kalnenieks, Inese Strazdina, Liene Patetko, Zane Lasa, Reinis Rutkis, Elza Kaktina   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Waste to resource: Mining antimicrobial peptides in sludge from metagenomes using machine learning

Environment International
The emergence of antibiotic-resistant bacteria poses a huge threat to the treatment of infections. Antimicrobial peptides are a class of short peptides that widely exist in organisms and are considered as potential substitutes for traditional antibiotics.
Jiaqi Xu, Xin Xu, Yunhan Jiang, Yulong Fu, Chaofeng Shen   +4 more
doaj   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source