Results 51 to 60 of about 801,510 (301)

Effects of Cations and PH on Antimicrobial Activity of Thanatin and s-Thanatin against _Escherichia coli_ ATCC25922 and _B. subtilis_ ATCC 21332 [PDF]

, 2008
Thanatin and s-thanatin were insect antimicrobial peptides which have shown potent antimicrobial activities on a variety of microbes. In order to investigate the effect of cations and pH on the activity of these peptides against Gram-negative bacteria ...
Zilong Shen, Xiaobo Fan, Rui Zhao, Guoqiu Wu, Hui Li, Linxian Li, Jiaxuan Ding   +6 more
core  

Waste to resource: Mining antimicrobial peptides in sludge from metagenomes using machine learning

Environment International
The emergence of antibiotic-resistant bacteria poses a huge threat to the treatment of infections. Antimicrobial peptides are a class of short peptides that widely exist in organisms and are considered as potential substitutes for traditional antibiotics.
Jiaqi Xu, Xin Xu, Yunhan Jiang, Yulong Fu, Chaofeng Shen   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs [PDF]

, 2011
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates and/or food additives. They are present in many organisms including bacteria, insects, fish and mammals.
O\u27Brien, Peter J., David J. Brayden, Baird, Alan W., Peter J. O’Brien, Marc Devocelle, Devocelle, Marc, Sam Maher, Alan W. Baird, Maher, Sam, Edwin G. Walsh, Walsh, Edwin G., O'Brien, Peter J., Brayden, David James   +12 more
core   +1 more source

Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS

Frontiers in Pharmacology, 2021
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimicrobial activity. Here, two proline-rich peptides (consP1: VRKPPYLPRPRPRPL-CONH2 and
Kai Hilpert, Jurnorain Gani, Christoph Rumancev, Nathan Simpson, Paula Matilde Lopez-Perez, Vasil M. Garamus, Andreas Robert von Gundlach, Petar Markov, Marco Scocchi, Ralf Mikut, Axel Rosenhahn   +10 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Antimicrobial Peptides in Cutaneous Wound Healing

, 2016
Injury that breached the physical skin barrier increases the likelihood of infection. The wound healing process is divided into hemostasis, inflammation, proliferation, and tissue remodeling. Antimicrobial peptides play a major role for the antimicrobial
Sørensen, Ole E,, Lund University.
core   +1 more source

Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptide Sequences with rAMPage [PDF]

, 2022
Antibiotic resistance is a global health crisis increasing in prevalence every day. To combat this crisis, alternative antimicrobial therapeutics are urgently needed.
Diana Lin, Coombe, Lauren, Louie, Nathan, Caren C. Helbing, Sambina Islam Aninta, René L. Warren, Birol, Inanc, Nip, Ka Ming, Ka Ming Nip, Anat Yanai, Lauren Coombe, Linda M. N. Hoang, Helbing, Caren C., Inanc Birol, Lin, Diana, Yanai, Anat, Nathan Louie, Hoang, Linda M. N., Darcy Sutherland, Warren, René L., Li, Chenkai, Sutherland, Darcy, Aninta, Sambina Islam, Chenkai Li   +23 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Functional divergence among silkworm antimicrobial peptide paralogs by the activities of recombinant proteins and the induced expression profiles. [PDF]

PLoS ONE, 2011
Antimicrobial peptides are small-molecule proteins that are usually encoded by multiple-gene families. They play crucial roles in the innate immune response, but reports on the functional divergence of antimicrobial peptide gene families are rare.
Wanying Yang, Tingcai Cheng, Mingqiang Ye, Xiaojuan Deng, Huiyu Yi, Yadong Huang, Xiang Tan, Dong Han, Bo Wang, Zhonghuai Xiang, Yang Cao, Qingyou Xia   +11 more
doaj   +1 more source