Results 11 to 20 of about 126,899 (260)
Pharmaceuticals, 2013 The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents.
Ali Adem Bahar, Dacheng Ren
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Antimicrobial Peptides in Reptiles [PDF]
Pharmaceuticals, 2014 Reptiles are among the oldest known amniotes and are highly diverse in their morphology and ecological niches. These animals have an evolutionarily ancient innate-immune system that is of great interest to scientists trying to identify new and useful ...
Monique L. van Hoek
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Antimicrobial and Antibiofilm Peptides [PDF]
Biomolecules, 2020 The increasing onset of multidrug-resistant bacteria has propelled microbiology research towards antimicrobial peptides as new possible antibiotics from natural sources.
Angela Di Somma +4 more
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Current Biology, 2016 Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells.
Zhang, Ling-juan, Gallo, Richard L.
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Antimicrobial Peptides in Action [PDF]
Journal of the American Chemical Society, 2006 Molecular dynamics simulations of the magainin MG-H2 peptide interacting with a model phospholipid membrane have been used to investigate the mechanism by which antimicrobial peptides act. Multiple copies of the peptide were randomly placed in solution close to the membrane.
Leontiadou, H. +2 more
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Psoriasis and Antimicrobial Peptides [PDF]
International Journal of Molecular Sciences, 2020 Psoriasis is a systemic inflammatory disease caused by crosstalk between various cells such as T cells, neutrophils, dendritic cells, and keratinocytes. Antimicrobial peptides (AMPs) such as β-defensin, S100, and cathelicidin are secreted from these cells and activate the innate immune system through various mechanisms to induce inflammation, thus ...
Toshiya Takahashi, Kenshi Yamasaki
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Antimicrobial Peptides in 2014 [PDF]
Pharmaceuticals, 2015 This article highlights new members, novel mechanisms of action, new functions, and interesting applications of antimicrobial peptides reported in 2014. As of December 2014, over 100 new peptides were registered into the Antimicrobial Peptide Database, increasing the total number of entries to 2493.
Guangshun Wang +5 more
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Antimicrobial peptides and pregnancy [PDF]
Reproduction, 2011 Abstract Antimicrobial peptides (AMPs) are small proteins produced by epithelial surfaces and inflammatory cells, which have broad-spectrum antimicrobial and immunomodulatory activities. They are known to be important in a number of infectious and inflammatory conditions and have been shown to be present in a number of sites ...
Lorraine, Frew, Sarah J, Stock
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Plant antimicrobial peptides [PDF]
Folia Microbiologica, 2013 Plant antimicrobial peptides (AMPs) are a component of barrier defense system of plants. They have been isolated from roots, seeds, flowers, stems, and leaves of a wide variety of species and have activities towards phytopathogens, as well as against bacteria pathogenic to humans.
Nawrot, Robert +5 more
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De novo peptides as potential antimicrobial agents
Heliyon, 2023 The phenomenon of antimicrobial resistance threatens our ability to treat common infections. The clinical pipeline for new antimicrobials is pretty much dry and hence, there is a need for the development of new antimicrobial agents with low toxicities to
Margaret Amerley Amarh +2 more
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