Results 11 to 20 of about 151,205 (306)

Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]

Frontiers in Microbiology, 2021
Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides
Ran Wu, Jiri Patocka, Jiri Patocka, Eugenie Nepovimova, Patrik Oleksak, Martin Valis, Wenda Wu, Wenda Wu, Kamil Kuca, Kamil Kuca   +9 more
doaj   +3 more sources

Antimicrobial Peptides in Reptiles [PDF]

Pharmaceuticals, 2014
Reptiles are among the oldest known amniotes and are highly diverse in their morphology and ecological niches. These animals have an evolutionarily ancient innate-immune system that is of great interest to scientists trying to identify new and useful ...
Monique L. van Hoek
doaj   +3 more sources

Probing protein sequences as sources for encrypted antimicrobial peptides. [PDF]

PLoS ONE, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Guilherme D Brand, Mariana T Q Magalhães, Maria L P Tinoco, Francisco J L Aragão, Jacques Nicoli, Sharon M Kelly, Alan Cooper, Carlos Bloch   +7 more
doaj   +2 more sources

Peptide Stapling Applied to Antimicrobial Peptides

Antibiotics, 2023
Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço, Thuanny Borba Rios, Állan Pires da Silva, Octávio Luiz Franco, Marcelo Henrique Soller Ramada   +4 more
openaire   +4 more sources

Peptides and Peptidomimetics for Antimicrobial Drug Design

Pharmaceuticals, 2015
The purpose of this paper is to introduce and highlight a few classes of traditional antimicrobial peptides with a focus on structure-activity relationship studies.
Biljana Mojsoska, Håvard Jenssen
doaj   +3 more sources

Perspective: A proposal on solutions of modern supply chain construction for lactoferrin

Journal of Dairy Science, 2023
: Lactoferrin is an iron-binding glycoprotein of the transferrin family that is found in most bodily fluids of mammals and has a variety of biological and beneficial functions, with great importance in health enhancement as a supplement for humans and ...
Ruoyu Mao, Xuanxuan Ma, Ya Hao, Guihong Pen, Xueling Zheng, Na Yang, Da Teng, Jianhua Wang   +7 more
doaj   +1 more source

Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model

Frontiers in Microbiology, 2022
Staphylococcus aureus (S. aureus) is one of the most common pathogenic bacteria responsible for causing a life-threatening peritonitis disease. NZX, as a variant of fungal defensin plectasin, displayed potent antibacterial activity against S. aureus.
Xueling Zheng, Xueling Zheng, Xueling Zheng, Na Yang, Na Yang, Na Yang, Ruoyu Mao, Ruoyu Mao, Ruoyu Mao, Ya Hao, Ya Hao, Ya Hao, Da Teng, Da Teng, Da Teng, Jianhua Wang, Jianhua Wang, Jianhua Wang   +17 more
doaj   +1 more source

Plectasin: from evolution to truncation, expression, and better druggability

Frontiers in Microbiology, 2023
Non-computational classical evolution analysis of plectasin and its functional relatives can especially contribute tool value during access to meet requirements for their better druggability in clinical use.
Xuan Li, Xuan Li, Xuan Li, Ya Hao, Ya Hao, Ya Hao, Na Yang, Na Yang, Na Yang, Ruoyu Mao, Ruoyu Mao, Ruoyu Mao, Da Teng, Da Teng, Da Teng, Jianhua Wang, Jianhua Wang, Jianhua Wang   +17 more
doaj   +1 more source

Targeted antimicrobial peptides [PDF]

Frontiers in Immunology, 2012
The existence of natural antimicrobial substances, contributing to the mechanisms of host defenses, has been recognized since the late nineteenth century. In 1963, the in vitro antibacterial activity of leukocyte extracts was attributed to basic proteins.
Marc eDevocelle
doaj   +3 more sources

Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis

Antibiotics, 2022
Antibiotic resistance is a global threat and requires the search for new treatment strategies. Natural antimicrobial peptides (AMPs) have pronounced antibacterial, antiviral, antifungal, and antitumor activity.
Albert Bolatchiev, Vladimir Baturin, Elizaveta Bolatchieva   +2 more
doaj   +1 more source