In Silico Structural Evaluation of Short Cationic Antimicrobial Peptides [PDF]
Pharmaceutics, 2018 Cationic peptides with antimicrobial properties are ubiquitous in nature and have been studied for many years in an attempt to design novel antibiotics.
Ilaria Passarini +3 more
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Cationic Antimicrobial Peptides Inactivate Shiga Toxin-Encoding Bacteriophages [PDF]
Frontiers in Chemistry, 2017 Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections. We have previously reported the inactivation of bacteriophage encoding Stx after treatment with chitosan, a linear polysaccharide polymer
Manuel E. Del Cogliano +13 more
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Antimicrobial activity of cationic antimicrobial peptides against stationary phase bacteria
Frontiers in Microbiology, 2022 Antimicrobial peptides (AMPs) are ancient antimicrobial weapons used by multicellular organisms as components of their innate immune defenses. Because of the antibiotic crisis, AMPs have also become candidates for developing new drugs. Here, we show that
Alexandro Rodríguez-Rojas +3 more
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Bacterial cell fate under stress: lipid remodeling and antimicrobial peptide attack [PDF]
npj Antimicrobials and ResistanceDynamic changes in lipid membrane composition are a common response to stress, often involving shifts in key lipid molecules. Phosphatidic acid (PA), a central precursor in lipid biosynthesis, accumulates when anionic phospholipid synthesis is blocked ...
Djenana Vejzovic +5 more
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Multifaceted antimicrobial mechanisms of NCR147-derived peptides from Medicago truncatula [PDF]
Frontiers in MicrobiologyIntroductionAntimicrobial peptides (AMPs), key components of innate immunity, offer broad-spectrum activity against diverse pathogens. In Medicago truncatula, over 700 nodule-specific cysteine-rich (NCR) peptides with highly diverse sequences and ...
Hilda Tiricz +15 more
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Pep5-Cpp, a Cyclin D2-Derived Antimicrobial [PDF]
MoleculesPeptidomic studies in HeLa cells identified the antitumoral activity of Pep5, and our group observed that coupling Pep5 to a carrier peptide (Cpp) provides antimicrobial potential.
Bianca Silva Souto +8 more
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Cationic antimicrobial peptides: potential templates for anticancer agents
Frontiers in MedicineCancer is a major global health concern and one of the leading causes of death worldwide. According to the World Health Organization (WHO), there is an urgent need for novel therapeutic agents to treat this disease.
Yahson Fernando Varela-Quitián +2 more
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The significance of salivary cationic antimicrobial peptides in caries risk assessment in children: A literature review [PDF]
Acta Stomatologica Naissi, 2023 Introduction: Caries risk assessment is the essential step in the modern clinical approach to caries management. It is a basic prerequisite for the development of preventive measures and strategies for the primary prevention of caries. Its reliability is
Stojković Branislava B. +9 more
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Bioprospecting the American alligator (Alligator mississippiensis) host defense peptidome. [PDF]
PLoS ONE, 2015 Cationic antimicrobial peptides and their therapeutic potential have garnered growing interest because of the proliferation of bacterial resistance.
Barney M Bishop +9 more
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Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli. [PDF]
PLoS ONE, 2014 Minimum inhibitory concentrations (MICs) against E. coli were measured for three nylon-3 polymers using Luria-Bertani broth (LB), brain-heart infusion broth (BHI), and a chemically defined complete medium (EZRDM).
Heejun Choi +4 more
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