Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates [PDF]
, 2013 Antibiotic resistance is one of the main problems concerning public health or clinical practice. Antimicrobial peptides appear as good candidates for the development of new therapeutic drugs.
Corso, Alejandra +7 more
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Antimicrobial peptides: agents of border protection for companion animals. [PDF]
, 2012 Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Symbiotic outcome modified by the diversification from 7 to over 700 nodule specific cysteine rich peptides [PDF]
, 2020 Legume-rhizobium symbiosis represents one of the most successfully co-evolved mutualisms. Within nodules, the bacterial cells undergo distinct metabolic and morphological changes and differentiate into nitrogen-fixing bacteroids.
Achom, Mingkee +4 more
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Antimicrobial activity and synergistic effect of phage-encoded antimicrobial peptides with colistin and outer membrane permeabilizing agents against Acinetobacter baumannii [PDF]
PeerJBackground Acinetobacter baumannii poses a significant public health threat. Phage-encoded antimicrobial peptides (AMPs) have emerged as promising candidates in the battle against antibiotic-resistant A. baumannii. Methods Antimicrobial peptides from the
Punnaphat Rothong +9 more
doaj +2 more sources
Recent advances in the field of antimicrobial peptides in inflammatory diseases
Advanced Biomedical Research, 2013 Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
doaj +1 more source
New amphiphilic amino acid derivatives for efficient DNA transfection in vitro [PDF]
, 2017 Nucleic acids-based therapies have recently developed as next-generationagents for treating and preventing viral infection, cancer, and genetic disorders,but their use is still limited due to its relatively poor delivery into targetedcells.
Antuña, Sebastián +7 more
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Engineering Approaches for the Development of Antimicrobial Peptide-Based Antibiotics
Antibiotics, 2022 Antimicrobial peptides (AMPs) have received increasing attention as potential alternatives for future antibiotics because of the rise of multidrug-resistant (MDR) bacteria.
Su-Jin Kang, So Hee Nam, Bong-Jin Lee
doaj +1 more source
Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]
, 2014 Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna +56 more
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Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
Frontiers in Microbiology, 2013 Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast potential as peptide-based drugs. Great effort has been made in order to exploit their mechanisms of action, aiming to identify their targets as well as to enhance their ...
Kelly eMulder +4 more
doaj +1 more source
Small cationic antimicrobial peptides delocalize peripheral membrane proteins [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance Multidrug-resistant bacteria present an acute problem to medicine, generating interest in novel antimicrobial strategies. Antimicrobial peptides currently are being investigated, both as antibiotics and as immunomodulatory agents. Many antimicrobial peptides interact with the bacterial membrane, a previously underexplored
Michaela, Wenzel +17 more
openaire +2 more sources