Results 31 to 40 of about 53,767 (297)
Pharmaceuticals, 2013 Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines.
Margitta Dathe +4 more
doaj +1 more source
Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis [PDF]
Journal of Bacteriology, 2005 ABSTRACT Cationic antimicrobial peptides (CAMPs) are important components of the innate host defense system against microbial infections and microbial products. However, the human pathogen Neisseria meningitidis is intrinsically highly resistant to CAMPs, such as polymyxin B (PxB) (MIC ≥ 512 μg/ml).
Yih-Ling, Tzeng +6 more
openaire +2 more sources
Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]
, 2017 Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi +10 more
core +3 more sources
Interaction of Cationic Antimicrobial Peptides with Model Membranes [PDF]
Journal of Biological Chemistry, 2001 A series of natural and synthetic cationic antimicrobial peptides from various structural classes, including alpha-helical, beta-sheet, extended, and cyclic, were examined for their ability to interact with model membranes, assessing penetration of phospholipid monolayers and induction of lipid flip-flop, membrane leakiness, and peptide translocation ...
L, Zhang, A, Rozek, R E, Hancock
openaire +2 more sources
Antibiotics, 2023 Here we designed and synthesized analogs of two antimicrobial peptides, namely C10:0-A2, a lipopeptide, and TA4, a cationic α-helical amphipathic peptide, and used non-proteinogenic amino acids to improve their therapeutic properties. The physicochemical
Maria Veronica Humpola +6 more
doaj +1 more source
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
Antimicrobial peptides: the role of hydrophobicity in the alpha helical structure [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2013 The antimicrobial peptides (AMPs) are a class of molecule obtained from plants, insects, animals, and humans. These peptides have been classified into five categories: 1. Anionic peptide, 2. Linear alpha helical cationic peptide, 3.
Pandurangan Perumal, Vijaya P. Pandey
doaj
Functions of Cationic Host Defense Peptides in Immunity
Pharmaceuticals, 2016 Cationic host defense peptides are a widely distributed family of immunomodulatory molecules with antimicrobial properties. The biological functions of these peptides include the ability to influence innate and adaptive immunity for efficient resolution ...
Mahadevappa Hemshekhar +2 more
doaj +1 more source
Frontiers in Immunology, 2020 Cationic antimicrobial peptides (AMPs) are active immune effectors of multicellular organisms and are also considered as new antimicrobial drug candidates.
Alexandro Rodríguez-Rojas +8 more
doaj +1 more source
Antibacterial activity of active peptide from marine macroalgae Chondrus crispus protein hydrolysate against Staphylococcus aureus [PDF]
Pharmacia, 2023 Macroalgae is a protein source with the potential to yield antimicrobial peptides (AMPs) that exhibit a wide range of biological activities. This study aimed to find bioactive peptide-based antibacterial compounds from marine macroalgae Chondrus crispus ...
Ahmad Habibie +3 more
doaj +3 more sources