Results 31 to 40 of about 28,103 (254)

Collectins and Cationic Antimicrobial Peptides of the Respiratory Epithelia [PDF]

Veterinary Pathology, 2006
The respiratory epithelium is a primary site for the deposition of microorganisms that are acquired during inspiration. The innate immune system of the respiratory tract eliminates many of these potentially harmful agents preventing their colonization.
Grubor, Branka, Meyerholz, David, Ackermann, Mark   +2 more
openaire   +3 more sources

Racing on the Wrong Track

Frontiers in Chemistry, 2017
The preclinical in vitro and in vivo benchmark figures of cationic antimicrobial peptides have to be revisited based on the newly discovered alternative modes of action.
Laszlo Otvos, Laszlo Otvos
doaj   +1 more source

Identification of New Ocellatin Antimicrobial Peptides by cDNA Precursor Cloning in the Frame of This Family of Intriguing Peptides

Antibiotics, 2020
Ocellatins are a family of antimicrobial peptides found exclusively in the Leptodactylus genus. To date, 10 species have been studied and more than 23 peptides described.
Mariela M. Marani, Silvana Aguilar, Ana P. Cuzziol Boccioni, Natalia L. Cancelarich, Néstor G. Basso, Fernando Albericio   +5 more
doaj   +1 more source

Binding of cationic analogues of α-MSH to lipopolysaccharide and disruption of the cytoplasmic membranes caused bactericidal action against Escherichia coli

Scientific Reports, 2022
In earlier reports, we have shown the antimicrobial activity of a host neuropeptide, alpha-melanocyte stimulating hormone (α-MSH) and its cationic analogues against Staphylococcus aureus.
Kanchan Tiwari, Madhuri Singh, Prince Kumar, Kasturi Mukhopadhyay   +3 more
doaj   +1 more source

Interaction of cationic antimicrobial peptides with Mycoplasma pulmonis [PDF]

FEBS Letters, 2013
We investigated the mode of action underlying the anti‐mycoplasma activity of cationic antimicrobial peptides (AMPs) using four known AMPs and Mycoplasma pulmonis as a model mycoplasma. Scanning electron microscopy revealed that the integrity of the M.
Park, Ho Jin, Kang, Ki Mo, Dybvig, Kevin, Lee, Bok Luel, Jung, Yong Woo, Lee, In Hee   +5 more
openaire   +2 more sources

Short, Synthetic Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with Antibiotics

Antibiotics, 2015
Multicellular organisms are constantly exposed to a multitude of pathogenic microbes. Infection is inhibited in vivo by the innate and adaptive immune system. Mycobacterium species have emerged that are resistant to most antibiotics.
Kajal Gupta, Sameer Singh, Monique L. van Hoek   +2 more
doaj   +1 more source

Antimicrobials, stress and mutagenesis.

PLoS Pathogens, 2014
Cationic antimicrobial peptides are ancient and ubiquitous immune effectors that multicellular organisms use to kill and police microbes whereas antibiotics are mostly employed by microorganisms.
Alexandro Rodríguez-Rojas, Olga Makarova, Jens Rolff   +2 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities

Molecules, 2020
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic molecules produced by prokaryotic and eukaryotic organisms that play a key role in the innate immune defense against viruses, bacteria and fungi.
Anna Lucia Tornesello, Antonella Borrelli, Luigi Buonaguro, Franco Maria Buonaguro, Maria Lina Tornesello   +4 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source