Results 41 to 50 of about 28,103 (254)
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Opposing effects of cationic antimicrobial peptides and divalent cations on bacterial lipopolysaccharides [PDF]
Physical Review E, 2017 The permeability of the bacterial outer membrane, enclosing Gram-negative bacteria, depends on the interactions of the outer, lipopolysaccharide (LPS) layer, with surrounding ions and molecules. We present a coarse-grained model for describing how cationic amphiphilic molecules (e.g., antimicrobial peptides) interact with and perturb the LPS layer in a
Smart, Matthew +3 more
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Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Advanced Materials, EarlyView.Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
The Characterization of Two-Component System PmrA/PmrB in Cronobacter sakazakii
Frontiers in Microbiology, 2020 Cronobacter sakazakii is an opportunistic Gram-negative pathogen that could cause meningitis and necrotizing enterocolitis. Several Gram-negative bacteria use the PmrA/PmrB system to sense and adapt to environmental change by resistance to cationic ...
Jingjing Hua +3 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source
Complex precursor structures of cytolytic cupiennins identified in spider venom gland transcriptomes
Scientific Reports, 2021 Analysis of spider venom gland transcriptomes focuses on the identification of possible neurotoxins, proteins and enzymes. Here, the first comprehensive transcriptome analysis of cupiennins, small linear cationic peptides, also known as cytolytic or ...
Lucia Kuhn-Nentwig
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NMR assisted studies on the solution structures and functions of antimicrobial peptides
Magnetic Resonance Letters, 2022 Microbial resistance has now become a global public health concern, and the spread of multidrug-resistant bacteria also threatens human health. Antimicrobial peptides (AMPs) are a class of small peptides with antibacterial, anti-inflammatory, anti ...
Yaying Zhang, Chunyang Cao
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3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Advanced Materials Technologies, EarlyView.Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source
Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics
Molecules, 2017 Cyclic peptides are receiving significant attention thanks to their antimicrobial activity and high serum stability, which is useful to develop and design novel antimicrobial agents.
Annarita Falanga +6 more
doaj +1 more source
Antimicrobial activity of cationic peptides in endodontic procedures
European Journal of Dentistry, 2014 ABSTRACT Objectives: The present study aimed to investigate the antimicrobial and biofilm inhibition activity of synthetic antimicrobial peptides (AMPs) against microbes such as Enterococcus faecalis, Staphylococcus aureus, and Candida albicans which are involved in endodontic infections. Materials and Methods: Agar diffusion test was done to
Winfred, Sofi Beaula +6 more
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