Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C. +3 more
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C-PAmP: large scale analysis and database construction containing high scoring computationally predicted antimicrobial peptides for all the available plant species. [PDF]
BACKGROUND: Antimicrobial peptides are a promising alternative to conventional antibiotics. Plants are an important source of such peptides; their pharmacological properties are known since antiquity.
Anastasia Niarchou +3 more
doaj +1 more source
Analysis and Prediction of some Histone-derived Antimicrobial Peptides from Toads Duttaphrynus melanostictus and Phyrinoidis asper [PDF]
Antimicrobial peptides in skin secretions of toads is a promising methods to combat a wide spectrum of bacteria. Histone H2A is a type of DNA-binding protein that acts as a precursor for several antimicrobial peptides. In toads (family Bufonidae) buforin
Muhammad Dailami +2 more
doaj +1 more source
De novo peptides as potential antimicrobial agents
The phenomenon of antimicrobial resistance threatens our ability to treat common infections. The clinical pipeline for new antimicrobials is pretty much dry and hence, there is a need for the development of new antimicrobial agents with low toxicities to
Margaret Amerley Amarh +2 more
doaj +1 more source
Mechanisms of Antimicrobial Peptides from Bagasse against Human Pathogenic Bacteria
Nonedible agricultural wastes (agricultural wastes, agro-industrial wastes, and fishery wastes) were chosen as potential sources of antimicrobial peptides and evaluated for antibacterial efficiency against human pathogens.
Narumon Phaonakrob +2 more
core +1 more source
Modified CLEC3A-Derived Antimicrobial Peptides Lead to Enhanced Antimicrobial Activity against Drug-Resistant Bacteria [PDF]
Antimicrobial peptides (AMPs) represent a promising alternative to conventional antibiotics. Sequence changes can significantly improve the therapeutic properties of antimicrobial peptides.
Dzemal Elezagic +17 more
core +1 more source
Targeting Multidrug Resistance With Antimicrobial Peptide-Decorated Nanoparticles and Polymers
As a category of small peptides frequently found in nature, antimicrobial peptides (AMPs) constitute a major part of the innate immune system of various organisms. Antimicrobial peptides feature various inhibitory effects against fungi, bacteria, viruses,
Solmaz Maleki Dizaj +6 more
doaj +1 more source
Application of Artificial Intelligence Algorithms in the Field of Antimicrobial Peptide Prediction [PDF]
Antimicrobial peptides, as small molecular peptides with extensive antibacterial activity, have shown great potential in food preservation and other fields because of their unique antibacterial mechanism.
QIAN Yuchen, NIE Ting, HUA Yanming, XU Shiying, GUO Sheng, ZHANG Xin, LUO Xiaohu, LIU Yanan
doaj +1 more source
Design and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an amphipathic α-helical head and an aromatic tail.
Ziyi Tang +13 more
doaj +1 more source
Molecular genetic design strategies for improving stability of feed antimicrobial peptides
Feeding antimicrobial peptides have a special physical membrane breaking bactericidal mechanism and are not easy to produce drug resistance. However, naturally occurring or self-designed antimicrobial peptides are faced with the problem of low ...
WANG Tao +7 more
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