Results 211 to 220 of about 454,292 (268)

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Antimicrobial effect of biological surgical mesh added with vancomycin or silver nanoparticles for multidrug-resistant bacteria: experimental study in rats. [PDF]

Rev Col Bras Cir
Loureiro MP, Novais PM, Padilha IT, Guérios MS, Crisigiovanni FL, Vieira VB, Masselai AL, Caravalho RM, Salamacha E, Zontta L, Gomes MDC, Boscardim EB, Andreguetto IU, Tuon FF.   +13 more
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Antimicrobial effect of curcumin, alone or in combination with black pepper, against foodborne pathogens in vacuum-packed ground mutton. [PDF]

Sci Rep
Elghareeb MA, Elshebrawy HA, Zaher HA, Sallam KI.   +3 more
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

The Antimicrobial Effect and ROS Redox Activity of Nb₂O₅-Containing Powders Obtained by the Sol-Gel Method. [PDF]

Gels
Ivanova K, Pavlova E, Ivanova I, Bachvarova-Nedelcheva A.   +3 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Comparative Evaluation of Antimicrobial Effect, Calcium Ion Release, and pH Change Using Herbal Combinations of Nanoparticle Calcium Hydroxide: An <i>In Vitro</i> Study. [PDF]

Int J Clin Pediatr Dent
Vijaya PS, Bethur SS, Somanna P, Sampath R.   +3 more
europepmc   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Antimicrobial Effect of Gentamicin/Heparin and Gentamicin/Citrate Lock Solutions on <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i> Clinical Strains. [PDF]

Infect Dis Rep
Salas-Treviño D, Rodríguez-Rodríguez AN, Ramírez-Elizondo MT, Padilla-Orozco M, Montoya-Hinojosa EI, Bocanegra-Ibarias P, Flores-Treviño S, Camacho-Ortiz A.   +7 more
europepmc   +1 more source