Results 101 to 110 of about 2,148,381 (250)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Phytochemical Profile and Biological Activities of Biscutella laevigata: A Comparative Study of Leaves, Seeds, and Microshoot Cultures

Applied Sciences
Biscutella laevigata (Brassicaceae) is an endemic species confined to European mountain regions, with a distribution range extending from the Iberian Peninsula through the Carpathians to the Balkans.
Marta Klimek-Szczykutowicz, Magdalena Anna Malinowska, Anna Śliwa, Ivica Blažević, Azra Ðulović, Karolina Wiśniewska, Renata Piwowarczyk, Paulina Paprocka, Małgorzata Wrzosek, Agnieszka Szopa   +9 more
doaj   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Combating antimicrobial resistance: Antimicrobial stewardship program in Taiwan

, 2014
Multi-drug-resistant organisms are increasingly recognized as a global public health issue. Healthcare-associated infection and antimicrobial resistance are also current challenges to the treatment of infectious diseases in Taiwan.
張上淳, Tseng, Shu-Hui;Lee, Chun-Ming;Lin, Tzou-Yien;Chang, Shan-Chwen;Chuang, Yin-Ching;Yen, Muh-Yong;Hwang, Kao-Pin;Leu, Hsieh-Shong;Yen, Che-Chieh;Chang, Feng-Yee   +1 more
core   +1 more source

Chemical Components, Emission Dynamics, and External Immune Functions of Red Palm Weevil Larval Volatiles in Response to Changes in Developmental Stages and Pathogen Stress

Insects
Chemical defenses help insects resist pathogen infection. The volatile compositions, emission patterns, and external immune functions of the red palm weevil (RPW), a major invasive pest now established in numerous countries including the Mediterranean ...
Can-Hui Ding, Wen-Qing You, Zong-Wei Zheng, Yu-Chen Pu, Li-Na Xu, You-Ming Hou, Yue Zhang, Cong Ou-Yang   +7 more
doaj   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Exploring the Nutritional Value and Bioactive Potential of Craterellus cornucopioides (L.) Pers. as a Functional Food Source

Foods
This study aimed to explore the phytochemical variability, nutrient composition, and bioactive profile of the edible mushroom species Craterellus cornucopioides with specimens originating from Romanian flora.
Mariana-Gabriela Bumbu, Mihaela Niculae, Irina Ielciu, Adela Pintea, Zsolt Matyas, Ștefan Alexandru Anton, Daniela Benedec, Melinda Fogarasi, Ioan Marcus, Oana Roșca-Casian, Nicodim Fiț, Daniela Hanganu   +11 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe, Giske CG, European Study Group on Antimicrobial Resistance Surveillance   +2 more
core   +1 more source