Results 1 to 10 of about 123,255 (260)

A novel combinatory treatment against a CDDP-resistant non-small cell lung cancer based on a Ruthenium(II)-cyclopentadienyl compound

Pharmacological Research
The therapeutic approach to many solid tumors, including non-small cell lung cancer (NSCLC), is mainly based on the use of platinum-containing anticancer agents and is often characterized by acquired or intrinsic resistance to the drug.
Iris C. Salaroglio, Denitsa Stefanova, Ricardo G. Teixeira, Nuno F.B. Oliveira, Amer Ahmed, Fabio Fusi, Virginia Tzankova, Yordan Yordanov, Miguel Machuqueiro, Simona Saponara, Andreia Valente, Chiara Riganti   +11 more
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Repair of a critical size defect in osteoporotic mice

Bone Reports, 2021
Franziska Strunz, Mark Siegrist, Nikola Saulacic, Marc Bohner, Willy Hofstetter   +4 more
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Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility

Drug Delivery
Methotrexate (MTX) is a folic acid antagonist routinely used in cancer treatment, characterized by poor water solubility and low skin permeability. These issues could be mitigated by using drug delivery systems, such as functionalized gold nanoparticles (
Denisse-Iulia Bostiog, Natalia Simionescu, Adina Coroaba, Ioana C. Marinas, Mariana C. Chifiriuc, Gratiela Gradisteanu Pircalabioru, Stelian S. Maier, Mariana Pinteala   +7 more
doaj   +1 more source

Solid-Binding Peptide for Enhancing Biocompatibility of Metallic Biomaterials

SynBio
Solid-binding peptides (SBPs) are a powerful tool for surface modification of metallic biomaterials which improve the biocompatibility and functionality of medical devices.
Satoshi Migita
doaj   +1 more source

Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene

Journal of Advanced Ceramics
Achieving synergy between mechanical and biological performance has long been a challenge in developing silicon nitride (Si3N4) as a bone regeneration implant material.
Zhe Zhan, Bin Deng, Yanru Chen, Xinghong Zhang, Jinzhu Song   +4 more
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Application of decellularization methods for scaffold production: advantages, disadvantages, biosafety and modifications

Frontiers in Bioengineering and Biotechnology
The development of efficient, biocompatible scaffolds is an actual challenge in tissue engineering. Scaffolds derived from animal sources offer promising structural and biochemical properties but require thorough decellularization to minimize ...
O. I. Shevchuk, O. I. Shevchuk, V. V. Korcheva, N. S. Moskalenko, V. M. Kyryk, V. M. Kyryk, K. V. Kot, D. S. Krasnienkov   +7 more
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Tailoring Polymeric Scaffolds with Buddleja globosa Extract for Dual Antimicrobial and Biocompatible Wound Healing Applications

Molecules
Integrating traditional herbal extracts into modern biomaterials offers a promising route for advanced wound care. A standardized Buddleja globosa Hope extract (BG-126), recognized for its therapeutic value, was incorporated into polymeric scaffolds with
Ricardo Ceriani, Daniel A. Cherif-Pino, Pamela Pérez-Basáez, Marcela Escobar, Patricio Leyton, Caroline R. Weinstein-Oppenheimer, Daniel F. Moraga-Espinoza, Tania F. Bahamondez-Canas   +7 more
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In Vivo investigation of xenotransplanted human blood-derived scaffold into mice as a biodegradable construct for improvement of pelvic floor repair

Frontiers in Bioengineering and Biotechnology
ObjectiveWe developed an autologous, novel human blood-derived scaffold (hBDS) to improve pelvic floor disorders. Both in vivo biocompatibility and biodegradation were investigated and compared by subcutaneous implantation, in the abdominal wall, and the
Fariba Behnia-Willison, Fariba Behnia-Willison, Pouria Aryan, Pouria Aryan, Mojdeh Salehnia, Mojdeh Salehnia, Mojdeh Salehnia, Nadia Willison, Nadia Willison, Tran T. T. Nguyen, Tran T. T. Nguyen, Nelson Tansu, Derek Abbott   +12 more
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Chemical Exposure, Risk of Multiple Chemical Sensitivity, and Occupational Safety

Safety and Health at Work, 2020
Paolo D. Pigatto, Anna Ronchi, Gianpaolo Guzzi   +2 more
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Mutagenicity Evaluation of Orthodontic Resins Using the Ames Test

Applied Sciences
The biocompatibility of orthodontic materials is crucial for patient safety, especially concerning their possible mutagenic effects. This study aimed to assess the mutagenic potential of three commercially available orthodontic resins using the Ames test.
Roberto Biagi, Gianna Dipalma, Federica Macrì, Niccolò Cenzato, Cinzia Maspero, Lucia Giannini   +5 more
doaj   +1 more source