Results 221 to 230 of about 119,446 (259)
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Disturbances of antimicrobial lipids in atopic dermatitis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2006SummaryPatients with atopic dermatitis exhibit an increased susceptibility to cutaneous infections, especially to pathological colonization with superantigen‐secreting Staphylococcus aureus. Recent attention has been focused on antimicrobial peptides, especially on cathelicidin and human β‐defensin‐2, which are under‐expressed in atopic skin ...
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The Antimicrobial Function of Milk lipids
2010Milk lipids serve not only as nutrients but as antimicrobial agents that constitute a defense system against microbial infections that occur at mucosal surfaces. The lipid fraction of milk develops antimicrobial activity in the gastrointestinal tract of suckling neonates as a result of lipolytic activity which converts milk triglycerides to ...
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Multiple lipid nanoparticles as antimicrobial drug delivery systems
Journal of Drug Delivery Science and Technology, 2022Abstract The present work aimed at investigating formulations based on multiple lipid nanoparticles (MLNs) containing carvacrol (CAR) and vancomycin hydrochloride (VAN) co-loaded (CAR-VAN-MLNs) as therapeutical strategy useful to improve the antibiotic activity of VAN.
Ben Khalifa R. +10 more
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Langmuir, 2016
The number of antibiotic-resistant bacteria is increasing worldwide, and the demand for novel antimicrobials is constantly growing. Antimicrobial peptides (AMPs) could be an important part of future treatment strategies of various bacterial infection diseases. However, AMPs have relatively low stability, because of proteolytic and chemical degradation.
Boge, Lucas +9 more
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The number of antibiotic-resistant bacteria is increasing worldwide, and the demand for novel antimicrobials is constantly growing. Antimicrobial peptides (AMPs) could be an important part of future treatment strategies of various bacterial infection diseases. However, AMPs have relatively low stability, because of proteolytic and chemical degradation.
Boge, Lucas +9 more
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2014
The most obvious function of the sebaceous gland is to excrete sebum [1, 2]. For a long time hyperseborrhea has been considered as a major etiopathogenetic factor for the development of acne. However, current research provides evidence that sebum quantity per se cannot be the only responsible factor, as demonstrated by the success of treatment with ...
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The most obvious function of the sebaceous gland is to excrete sebum [1, 2]. For a long time hyperseborrhea has been considered as a major etiopathogenetic factor for the development of acne. However, current research provides evidence that sebum quantity per se cannot be the only responsible factor, as demonstrated by the success of treatment with ...
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Bacterial membrane lipids in the action of antimicrobial agents
Journal of Peptide Science, 2010AbstractMany antimicrobial agents that target bacteria are cationic and can interact with the anionic lipid components that are exposed on the bacterial membrane. Bacteria vary widely in the nature of the major lipid components that are in the cell membrane.
Richard M, Epand, Raquel F, Epand
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Solvent-Free Microfluidic Fabrication of Antimicrobial Lipid Nanoparticles
ACS Applied Bio MaterialsAntimicrobial lipid nanoparticles composed of monoglycerides offer a promising strategy to inhibit membrane-enveloped viral and bacterial pathogens. However, previous efforts mainly focused on fabricating nanoparticles from long-chain monoglycerides, which lack intrinsic antimicrobial activity but contribute to nanoparticle stability and structural ...
Marta Ruano +6 more
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Antimicrobial lipids: Natural and synthetic fatty acids and monoglycerides
Lipids, 1977AbstractOver 40 natural or synthetic lipophilic compounds were screened for antimicrobial activity. Gram (+) bacteria and yeasts but not Gram (−) bacteria were affected by these agents. Epimino and selena fatty acids are more active than their corresponding straight chain unsubstituted fatty acids.
J. J. Kabara +2 more
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Modulation of Antimicrobial Peptide Potency in Stressed Lipid Bilayers
Physical Review Letters, 2019It is shown that the tendency of an archetypal antimicrobial peptide to insert into and perforate a simple lipid bilayer is strongly modulated by tensile stress in the membrane. The results, obtained through molecular dynamics simulations, have been demonstrated with several lipid compositions and appear to be general, although quantitative details ...
Valeria, Losasso +4 more
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Mechanistic Studies of Antimicrobial Peptides in Lipid Membranes
2021Antibiotics with unexplored mechanisms are needed to fight the alarming rise in antimicrobial resistance. Antimicrobial compounds targeting peptidoglycan precursor lipid II, the Achilles’ heel of bacteria, can be a suitable template. Therefore, structural studies of membrane mimetic models may provide insights regarding peptide-lipid interactions at ...
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