Results 141 to 150 of about 151,205 (306)

Characterization and Antimicrobial Activity of the Teleost Chemokine CXCL20b

, 2020
Fish are a potential source of diverse organic compounds with a broad spectrum of biological activities. Many fish-derived antimicrobial peptides and proteins are key components of the fish innate immune system.
Zhiwei Liao, Yanqi Zhang, Xun Xiao, Jianguo Su   +3 more
core   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

Nematode antimicrobial peptides [PDF]

Invertebrate Survival Journal, 2012
ISJ 9: 122-133, 2012 ISSN 1824-307XThere is currently insufficient data to determine the full spectrum of antimicrobial peptides (AMPs) that nematodes produce. Defensins, nemapores, cecropins, and caenacins/neuropeptide-like proteins have been identified,
DEK Tarr
doaj  

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Antibacterial and antiviral properties of Chenopodin-derived synthetic peptides [PDF]

Antimicrobial peptides have been developed based on plant-derived molecular scaffolds for the treatment of infectious diseases. Chenopodin is an abundant seed storage protein in quinoa, an An-dean plant with high nutritional and therapeutic properties ...
Pereira, Marília Gabriella A. G., Proaño-Bolaños, Carolina, Marcia L. Feijoo-Coronel, F. da Silva, José Maurício S., Diego Fernandes Lívio, José R. Almeida, Peña-Varas, Carlos, Carlos Peña-Varas, Fernandes Lívio, Diego, Lívio, Diego Fernandes, Marina Q. R. B. Rodrigues, Mendes, Bruno, de Oliveira, Leonardo Camilo, Mauro M. Teixeira, Bruno Mendes, Marília Gabriella A. G. Pereira, Monteros-Silva, Nina Q. Espinosa de los, Ketan Patel, Da Silva, José Maurício S. F., de Almeida, José R., Ramírez, David, Rodrigues, Marina Q. R. B., Patel, Ketan, José Antônio da Silva, Leonardo Camilo de Oliveira, Da Silva, José Antônio, Granjeiro, Paulo Afonso, Proaño Bolaños, Carolina, Nina Q. E. de los Monteros-Silva, Paulo Afonso Granjeiro, José Maurício S. F. da Silva, Feijoo-Coronel, Marcia L., Oliveira, Leonardo Camilo De, Almeida, José R., Espinosa de los Monteros Silva, Nina, Carolina Proaño-Bolaños, Vaiyapuri, Sakthi, G. Pereira, Marília Gabriella A., Vaiyapuri, Sakthivel, David Ramírez, Sakthivel Vaiyapuri, Teixeira, Mauro M., B. Rodrigues, Marina Q. R.   +42 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics

, 2008
Antimicrobial peptides (AMPs) are ubiquitous, gene-encoded natural antibiotics that have gained recent attention in the search for new antimicrobials to combat infectious disease.
Sang, Yongming, Blecha, Frank
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source