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Artificial Intelligence-Driven Discovery and Optimization of Antimicrobial Peptides Targeting ESKAPE Pathogens and Multidrug-Resistant Fungi. [PDF]
MicroorganismsWu-Mo C +5 more
europepmc +1 more source
Antimicrobial peptides for anticancer and antiviral therapy: last promising update. [PDF]
Discov OncolBahar A +3 more
europepmc +1 more source
Mapping the landscape of antimicrobial peptides in periodontology: A scoping review.
J Indian Soc PeriodontolPatil ND +4 more
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Dynamic exchange of antimicrobial peptides stabilize persistent lipid pores
Sengel J +4 more
europepmc +1 more source
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Surgical Infections, 2018
Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
Srinjoy Chakraborti, Sanjay Ram
openaire +3 more sources
Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
Srinjoy Chakraborti, Sanjay Ram
openaire +3 more sources
Journal of the American Academy of Dermatology, 2005
Antimicrobial peptides (AMPs) are small molecular weight proteins with broad spectrum antimicrobial activity against bacteria, viruses, and fungi. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid ...
Arash, Izadpanah, Richard L, Gallo
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Antimicrobial peptides (AMPs) are small molecular weight proteins with broad spectrum antimicrobial activity against bacteria, viruses, and fungi. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid ...
Arash, Izadpanah, Richard L, Gallo
openaire +3 more sources
Branched antimicrobial peptides
Russian Journal of Bioorganic Chemistry, 2007Branched peptides E(RLAR)2, E[E(RLAR)2]2, E(KLAR)2, and E[E(KLAR)2]2 were synthesized on the basis of tetrapeptides RLAR and KLAR and glutamic acid bis(pentafluorophenyl) ester. Their minimal antimicrobial concentrations were shown to decrease along with increase in branching, achieving 12 microM for Escherichia coli cells, which is comparable to ...
A Iu, Khrushchev +3 more
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Recent Patents on Anti-Infective Drug Discovery, 2018
After the era of serendipitous discovery of penicillin and outburst in the discovery and development of highly efficient antibiotics, a surge in resistance against the target specific drugs was observed, primarily due to a combination of selective pressure of antibiotics use and spontaneous mutations.
Komal, Sharma +3 more
openaire +2 more sources
After the era of serendipitous discovery of penicillin and outburst in the discovery and development of highly efficient antibiotics, a surge in resistance against the target specific drugs was observed, primarily due to a combination of selective pressure of antibiotics use and spontaneous mutations.
Komal, Sharma +3 more
openaire +2 more sources