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Antimicrobial Resistance: A Growing Serious Threat for Global Public Health

Healthcare, 2023
Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from ...
Md Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, J. Pawar, Naseem Akhter, A. Rabaan, M. Alqumber   +6 more
semanticscholar   +1 more source

Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021)

Antimicrobial Resistance and Infection Control, 2022
Background Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients hospitalized with COVID-19 which potentially acts as a catalyst for the ...
Ruwandi M. Kariyawasam, Danielle A. Julien, Dana C. Jelinski, Samantha L. Larose, Elissa Rennert-May, John M. Conly, Tanis C. Dingle, Justin Z. Chen, Gregory J. Tyrrell, Paul E. Ronksley, Herman W. Barkema   +10 more
doaj   +1 more source

Genetic and phenotypic characterizations of IncX3 plasmids harboring bla NDM-5 and bla NDM-16b in Japan

Microbiology Spectrum, 2023
The spread of the gene encoding the NDM-type carbapenemase, bla NDM, poses a serious threat to clinical practice and public health. This gene is usually carried by transferable plasmids, which facilitates its rapid spread among various species of ...
Hui Zuo, Yo Sugawara, Shizuo Kayama, Sayoko Kawakami, Koji Yahara, Motoyuki Sugai   +5 more
doaj   +1 more source

National genomic surveillance integrating standardized quantitative susceptibility testing clarifies antimicrobial resistance in Enterobacterales

Nature Communications, 2023
Antimicrobial resistance is a global health concern; Enterobacterales resistant to third-generation cephalosporins (3GCs) and carbapenems are of the highest priority.
Shizuo Kayama, Koji Yahara, Yo Sugawara, Sayoko Kawakami, Kohei Kondo, Hui Zuo, Shoko Kutsuno, Norikazu Kitamura, Aki Hirabayashi, Toshiki Kajihara, Hitomi Kurosu, Liansheng Yu, Masato Suzuki, Junzo Hisatsune, Motoyuki Sugai   +14 more
doaj   +1 more source

Genome-wide association studies reveal candidate genes associated to bacteraemia caused by ST93-IV CA-MRSA

BMC Genomics, 2021
Background The global emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has seen the dominance of specific clones in different regions around the world with the PVL-positive ST93-IV as the predominant CA-MRSA clone ...
Stanley Pang, Denise A Daley, Shafi Sahibzada, Shakeel Mowlaboccus, Marc Stegger, Geoffrey W Coombs   +5 more
doaj   +1 more source

AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence

Scientific Reports, 2021
Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable whole genome sequencing, in silico approaches to assessing AMR gene content can be used to detect known resistance mechanisms and potentially identify novel
M. Feldgarden, V. Brover, N. González-Escalona, J. Frye, Julie Haendiges, D. Haft, M. Hoffmann, J. Pettengill, Arjun B. Prasad, G. Tillman, G. Tyson, W. Klimke   +11 more
semanticscholar   +1 more source

Metals to combat antimicrobial resistance

Nature Reviews Chemistry, 2023
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific metal may be essential for survival yet toxic in certain forms and concentrations.
Angelo Frei, Anthony D. Verderosa, Alysha G. Elliott, J. Zuegg, M. Blaskovich   +4 more
semanticscholar   +1 more source

In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host

Nature Communications, 2021
Bordetella hinzii is an emerging pathogen with zoonotic risk to humans, known to be able to cause respiratory tract infection, bacteremia and endocarditis.
A. Launay, C.-J. Wu, A. Dulanto Chiang, J.-H. Youn, P. P. Khil, J. P. Dekker   +5 more
doaj   +1 more source

Antimicrobial Resistance (AMR)

British Journal of Biomedical Science, 2023
Antimicrobial resistance (AMR) has now emerged as a chronic public health problem globally, with the forecast of 10 million deaths per year globally by 2050.
Kashem Tang, B. Millar, J. Moore
semanticscholar   +1 more source

Antimicrobial Resistance in the Environment [PDF]

Water Environment Research, 2016
This review summarizes selected publications from 2017 highlighting the occurrence of antimicrobial resistance (AMR) genes in the environment with emphasis on the aquatic environment. The review also covers different treatment technologies being developed for AMR genes as an environmental contaminant. The progress made in the area of AMR gene databases
Robert D. Stedtfeld, Maggie R. Williams, Maggie R. Williams, Hassan Waseem, Syed A. Hashsham   +4 more
openaire   +6 more sources