Results 1 to 10 of about 410,913 (288)

Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021)

Antimicrobial Resistance and Infection Control, 2022
Background Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients hospitalized with COVID-19 which potentially acts as a catalyst for the ...
Ruwandi M. Kariyawasam, Danielle A. Julien, Dana C. Jelinski, Samantha L. Larose, Elissa Rennert-May, John M. Conly, Tanis C. Dingle, Justin Z. Chen, Gregory J. Tyrrell, Paul E. Ronksley, Herman W. Barkema   +10 more
doaj   +1 more source

National genomic surveillance integrating standardized quantitative susceptibility testing clarifies antimicrobial resistance in Enterobacterales

Nature Communications, 2023
Antimicrobial resistance is a global health concern; Enterobacterales resistant to third-generation cephalosporins (3GCs) and carbapenems are of the highest priority.
Shizuo Kayama, Koji Yahara, Yo Sugawara, Sayoko Kawakami, Kohei Kondo, Hui Zuo, Shoko Kutsuno, Norikazu Kitamura, Aki Hirabayashi, Toshiki Kajihara, Hitomi Kurosu, Liansheng Yu, Masato Suzuki, Junzo Hisatsune, Motoyuki Sugai   +14 more
doaj   +1 more source

Genetic and phenotypic characterizations of IncX3 plasmids harboring bla NDM-5 and bla NDM-16b in Japan

Microbiology Spectrum, 2023
The spread of the gene encoding the NDM-type carbapenemase, bla NDM, poses a serious threat to clinical practice and public health. This gene is usually carried by transferable plasmids, which facilitates its rapid spread among various species of ...
Hui Zuo, Yo Sugawara, Shizuo Kayama, Sayoko Kawakami, Koji Yahara, Motoyuki Sugai   +5 more
doaj   +1 more source

Antimicrobial resistance (AMR) [PDF]

European Journal of Hospital Pharmacy, 2019
The position paper of the European Association of Hospital Pharmacists (EAHP) highlights the importance of the prudent use of antimicrobial drugs through antibiotic stewardship to ensure efficient therapy for patients with life-threatening infections.
Steffen Amann, Kees Neef, Stephanie Kohl
openaire   +4 more sources

Genome-wide association studies reveal candidate genes associated to bacteraemia caused by ST93-IV CA-MRSA

BMC Genomics, 2021
Background The global emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has seen the dominance of specific clones in different regions around the world with the PVL-positive ST93-IV as the predominant CA-MRSA clone ...
Stanley Pang, Denise A Daley, Shafi Sahibzada, Shakeel Mowlaboccus, Marc Stegger, Geoffrey W Coombs   +5 more
doaj   +1 more source

In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host

Nature Communications, 2021
Bordetella hinzii is an emerging pathogen with zoonotic risk to humans, known to be able to cause respiratory tract infection, bacteremia and endocarditis.
A. Launay, C.-J. Wu, A. Dulanto Chiang, J.-H. Youn, P. P. Khil, J. P. Dekker   +5 more
doaj   +1 more source

An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis

Nature Communications, 2023
Bacteria possess elaborate systems to manage reactive oxygen and nitrogen species (ROS) arising from exposure to the mammalian immune system and environmental stresses.
Wei Lin Lee, Ameya Sinha, Ling Ning Lam, Hooi Linn Loo, Jiaqi Liang, Peiying Ho, Liang Cui, Cheryl Siew Choo Chan, Thomas Begley, Kimberly Ann Kline, Peter Dedon   +10 more
doaj   +1 more source

Comparative genotypic characterization related to antibiotic resistance phenotypes of clinical carbapenem-resistant Acinetobacter baumannii MTC1106 (ST2) and MTC0619 (ST25)

BMC Genomics, 2023
Background The prevalence of Acinetobacter baumannii in nosocomial infections and its remarkable ability to develop antimicrobial resistance have been a critical issue in hospital settings.
Made Rai Dwitya Wiradiputra, Krit Thirapanmethee, Piyatip Khuntayaporn, Pagakrong Wanapaisan, Mullika Traidej Chomnawang   +4 more
doaj   +1 more source

A viability assay combining palladium compound treatment with quantitative PCR to detect viable Mycobacterium avium subsp. paratuberculosis cells

Scientific Reports, 2022
Mycobacterium avium subsp. paratuberculosis (MAP) is a pathogenic bacterium causing the paratuberculosis, chronic and infectious disease common particularly in wild and domestic ruminants. Currently, culture techniques to detect viable MAP are still used
Martina Cechova, Monika Beinhauerova, Vladimir Babak, Petr Kralik   +3 more
doaj   +1 more source

Antimicrobial Resistance (AMR)

British Journal of Biomedical Science, 2023
Antimicrobial resistance (AMR) has now emerged as a chronic public health problem globally, with the forecast of 10 million deaths per year globally by 2050. AMR occurs when viruses, bacteria, fungi and parasites do not respond to antimicrobial treatments in humans and animals, thus allowing the survival of the microorganism within the host.
Tang, Ka Wah Kelly, Millar, Beverley C., Moore, John E.   +2 more
openaire   +2 more sources