Results 151 to 160 of about 752,331 (281)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

NIR‐Activated Ag2S Quantum Dots for Efficient Broad‐Spectrum Antibacterial and Biofilm Disruption

Advanced Materials Interfaces, EarlyView.
This study presents a novel non‐antibiotic strategy leveraging NIR‐activated Ag2S QDs for synergistic PTT/PDT. The platform degrades the protective extracellular matrix via localized hyperthermia, facilitating deep penetration and ROS‐induced oxidative damage.
Rui Yao, Peiqing Sun, Yaxin Chen, Zhijie Lei, Li Wang, Jianglin Yu, Ying Liu, Wusimanjiang Hailipitimu, Wei Wei, Jing Zhao, Xusheng Qiu   +10 more
wiley   +1 more source

Antimicrobial Resistance: The Answers. [PDF]

Br J Biomed Sci
Millar BC, Cates MJ, Torrisi MS, Round AJ, Warde A, Lowery CJ, Moore JE.   +6 more
europepmc   +1 more source

From Copper Nanoparticles to Alumina Encapsulated Porous Layers With Enhanced Mechanical Stability

Advanced Materials Interfaces, EarlyView.
This study analyzes the synthesis‐structure relation of individual Cu nanoparticles and highly porous nanoparticle‐based Cu films using different sputtering‐based nanoparticle sources. The inherent mechanical instability of the films is tackled with Al2O3 encapsulation through atomic layer deposition, enabling 4‐fold increase in critical force in ...
Dominik Gutnik, Daniele Casari, Laszlo Pethö, Michael Burtscher, Anna M. Hofer‐Roblyek, Christian Mitterer, Barbara Putz   +6 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Author Correction: National genomic surveillance integrating standardized quantitative susceptibility testing clarifies antimicrobial resistance in Enterobacterales

Nature Communications
Shizuo Kayama, Koji Yahara, Yo Sugawara, Sayoko Kawakami, Kohei Kondo, Hui Zuo, Shoko Kutsuno, Norikazu Kitamura, Aki Hirabayashi, Toshiki Kajihara, Hitomi Kurosu, Liansheng Yu, Masato Suzuki, Junzo Hisatsune, Motoyuki Sugai   +14 more
doaj   +1 more source

Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with precision medicine. [PDF]

Front Antibiot
Shinde A, Mohan A, Bulusu VM, Soni P, Singh J, Khadanga S, Joshi A, Venkatachalapathy P, Kanwar RK, Miraj SS, Munisamy M.   +10 more
europepmc   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Accelerating Discovery to Deployment: Argonne's Materials Engineering Research Facility (MERF) and Its Role in Scaling Materials Technologies for Water and Resource Solutions

Advanced Materials Technologies, EarlyView.
In this Perspective, we highlight the processing science and scale‐up capabilities of the Materials Engineering Research Facility (MERF) at the U.S. Department of Energy's Argonne National Laboratory, with an emphasis on practical solutions for sustainable water and critical resource recovery. We demonstrate how national laboratories bridge fundamental
Yuepeng Zhang, Bratin Sengupta, Xiaoao Shi, Haihui Pu, Jeffrey W. Elam, Gregory K. Krumdick, Jessica Durham Macholz, Allison Bennett Irion, Junhong Chen, Seth B. Darling   +9 more
wiley   +1 more source

ARKbase: Antimicrobial Resistance Knowledgebase1.0. [PDF]

Nucleic Acids Res
Gambhir S, Pandey S, Bajetha H, Kaur J, Das A, Pranavathiyani G, Aggarwal R, Maity U, Dange S, Singh V, Zarkar M, Sankhdher R, Singh B, Seth S, Bhardwaj A.   +14 more
europepmc   +1 more source