Results 11 to 20 of about 385,298 (294)

Coupled environmental and demographic fluctuations shape the evolution of cooperative antimicrobial resistance [PDF]

J. R. Soc. Interface 20, 20230393 (2023), 2023
There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can often be viewed as a cooperative behavior leading to the coexistence of resistant and sensitive cells in large ...
arxiv   +1 more source

High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Antimicrobial Resistance and Infection Control, 2022
Background Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide concern that demands immediate attention. Most information on AMR originates from high-income countries and little is known about the burden in Africa, particularly Nigeria ...
Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu, Folasade T. Ogunsola   +9 more
doaj   +1 more source

First Evidence of the Presence of the Causative Agent of Caseous Lymphadenitis—Corynebacterium pseudotuberculosis in Dairy Products Produced from the Milk of Small Ruminants

Pathogens, 2022
This study focused on the detection and quantification of selected bacteria and on the presence of enterotoxin genes in milk and dairy products from sheep and goat farms in the Czech Republic using quantitative real-time PCR (qPCR) and multiplex PCR (PCR)
Denisa Langova, Iva Slana, Jana Okunkova, Monika Moravkova, Martina Florianova, Jirina Markova   +5 more
doaj   +1 more source

Developing moral AI to support antimicrobial decision making [PDF]

, 2022
Artificial intelligence (AI) assisting with antimicrobial prescribing raises significant moral questions. Utilising ethical frameworks alongside AI-driven systems, while considering infection specific complexities, can support moral decision making to tackle antimicrobial resistance.
arxiv   +1 more source

Validation of Selective Agars for Detection and Quantification of Escherichia coli Strains Resistant to Critically Important Antimicrobials

Microbiology Spectrum, 2021
Success in the global fight against antimicrobial resistance (AMR) is likely to improve if surveillance can be performed on an epidemiological scale.
Zheng Z. Lee, Rebecca Abraham, Mark O’Dea, Ali Harb, Kelly Hunt, Terence Lee, Sam Abraham, David Jordan   +7 more
doaj   +1 more source

Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

BMC Infectious Diseases, 2020
Background Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mutations in the Quinolone Resistance
Mahdieh Sayadi, Hosna Zare, Saeed Amel Jamedar, Seyed Isaac Hashemy, Zahra Meshkat, Saman Soleimanpour, Sven Hoffner, Kiarash Ghazvini   +7 more
doaj   +1 more source

Development of a reference standard for the detection and quantification of Mycobacterium avium subsp. paratuberculosis by quantitative PCR

Scientific Reports, 2021
Quantitative PCR (qPCR) has become a frequently employed direct method for the detection and quantification of Mycobacterium avium subsp. paratuberculosis (MAP).
Monika Beinhauerova, Martina Beinhauerova, Sarah McCallum, Eric Sellal, Matteo Ricchi, Rory O’Brien, Beatrice Blanchard, Iva Slana, Vladimir Babak, Petr Kralik   +9 more
doaj   +1 more source

Antimicrobial Resistance of and Genomic Insights into Pasteurella multocida Strains Isolated from Australian Pigs

Microbiology Spectrum, 2023
Infection with Pasteurella multocida represents a significant economic threat to Australian pig producers, yet our knowledge of its antimicrobial susceptibilities is lagging, and genomic characterization of P.
Alec Truswell, Tanya J. Laird, Suzanna Jones, Mark O’Dea, John Blinco, Rebecca Abraham, Daniel Morison, David Jordan, David J. Hampson, Stanley Pang, Sam Abraham   +10 more
doaj   +1 more source

Resist or perish: fate of a microbial population subjected to a periodic presence of antimicrobial [PDF]

PLoS Comput. Biol.16(4): e1007798 (2020), 2019
The evolution of antimicrobial resistance can be strongly affected by variations of antimicrobial concentration. Here, we study the impact of periodic alternations of absence and presence of antimicrobial on resistance evolution in a microbial population, using a stochastic model that includes variations of both population composition and size, and ...
arxiv   +1 more source

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

Nature Communications, 2020
Whole-genome sequencing (WGS) can support drug resistance surveillance, but is rare in low- and middle-income countries. Here, the authors integrate WGS within the national antimicrobial resistance surveillance program in the Philippines and conduct a ...
Silvia Argimón, Melissa A. L. Masim, June M. Gayeta, Marietta L. Lagrada, Polle K. V. Macaranas, Victoria Cohen, Marilyn T. Limas, Holly O. Espiritu, Janziel C. Palarca, Jeremiah Chilam, Manuel C. Jamoralin, Alfred S. Villamin, Janice B. Borlasa, Agnettah M. Olorosa, Lara F. T. Hernandez, Karis D. Boehme, Benjamin Jeffrey, Khalil Abudahab, Charmian M. Hufano, Sonia B. Sia, John Stelling, Matthew T. G. Holden, David M. Aanensen, Celia C. Carlos   +23 more
doaj   +1 more source