Results 231 to 240 of about 4,619,553 (348)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Mechanisms of Bacterial Resistance and Innovative Strategies to Overcome Antimicrobial Resistance. [PDF]

Antibiotics (Basel)
Dini I.
europepmc   +1 more source

Homeopathy and antimicrobial resistance

Homeopathy, 2014
openaire   +2 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Dental devices and antimicrobial resistance: challenges, innovations, and regulatory compliances. [PDF]

Front Med Technol
Singh G, Singh M, Murali A, Gandhi S, Singh OV.   +4 more
europepmc   +1 more source

Disseminação de isolados de Enterobacteriaceae produtores da carbapenemase KPC-3 [PDF]

, 2014
Antimicrobial Resistance Surveillance Program in Portugal, Caniça, Manuela, Ferreira, Eugénia, Louro, Deolinda, Manageiro, Vera   +4 more
core  

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

Advanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi, Nian Liu, Jingyi Gu, Yinling Wang, Weiye Wang, Zhiwei Ke, Mingjun Xie, Wenjing Jin, Weicheng Kong, Jue Shi, Hui Pan, Yong He, Zhijian Xie   +12 more
wiley   +1 more source

The Global Impact of Bacterial Antimicrobial Resistance: Addressing Gaps and Future Strategies. [PDF]

Public Health Chall
Jamil S, Harun MGD, Biswas MS, Abdulrahim A, Chaudhary N, Adepoju VA, Khan HTA, Adebayo UO.   +7 more
europepmc   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Antimicrobial Resistance in <i>Rhodococcus equi</i> and the Promise of Synergistic Therapies. [PDF]

Antibiotics (Basel)
Javadimarand F, Castañera P, Lorente-Torres B, Mortazavi N, Llano-Verdeja J, Fernández-Martínez S, Ferrero HÁ, Mateos LM, Mourenza Á, Letek M.   +9 more
europepmc   +1 more source