Results 271 to 280 of about 3,822,401 (336)

Concise communication title: wide adoption of rapid molecular detection of antimicrobial resistance markers for use with blood cultures: implications for national surveillance of antimicrobial resistance. [PDF]

Infect Control Hosp Epidemiol
Wu H, England R, Huang X, Lutgring J, Spinosa J, Fields V, Webb A, McMeen M, Benin A.   +8 more
europepmc   +1 more source

Healthcare Workers’ Knowledge, Awareness, and Practices Regarding Antimicrobial Use, Resistance, and Stewardship in Saudi Arabia

Mahmoud Abdallah, Osaid Al Meanazel, Mohammed Alruwaili, Hayam AlRasheed, Mahmoud Abdallah, Osaid Al Meanazel, Mohammed Alruwaili, Hayam AlRasheed   +7 more
openalex   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Bacterial Agents and Antimicrobial-Resistance Patterns in Canine Otitis Externa. [PDF]

Animals (Basel)
Saraiva S, Saraiva S, Calouro R, de Sousa T, Dapkevicius MLE, Mesquita JR, Coelho AC, Poeta P.   +7 more
europepmc   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

Harnessing phages to tackle antimicrobial resistance: a Saudi Arabian perspective. [PDF]

Front Cell Infect Microbiol
Alrafaie A.
europepmc   +1 more source

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, EarlyView.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

Healthcare providers' perspectives on antimicrobial resistance in Northwest Syria: an exploratory qualitative study. [PDF]

Front Public Health
Alkabbani H, Dahab M, Zakaria W, Hmeideh A, Almhawish N, Karah N, Abbara A.   +6 more
europepmc   +1 more source

Genomic characterization of an environmental Burkholderia thailandensis strain from Kerala, India reveals virulence and antimicrobial resistance signatures

Athira Santhosh, Parasmal Suresh, Sanjayan Arinarayanan, Lalitha Biswas, Pankaj Kumar Jha, Harisree Sudersanan, Raja Biswas, Arun Sachu, Hridya Vikraman, Divya Vijayakumar, Harpreet Kaur, Chiranjay Mukhopadhyay, Anil Kumar, Athira Santhosh, Parasmal Suresh, Sanjayan Arinarayanan, Lalitha Biswas, Pankaj Kumar Jha, Harisree Sudersanan, Raja Biswas, Arun Sachu, Hridya Vikraman, Divya Vijayakumar, Harpreet Kaur, Chiranjay Mukhopadhyay, Anil Kumar   +25 more
openalex   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source