Results 41 to 50 of about 761,259 (292)

Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]

open access: yes, 2015
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D.   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]

open access: yes, 2018
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina   +10 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Unveiling the Rare: Sternoclavicular Joint Brucellosis Osteomyelitis—A Case Report and Literature Review

open access: yesCase Reports in Infectious Diseases
Brucellosis, an endemic zoonotic infection, often presents with musculoskeletal complications, but sternoclavicular joint (SCJ) osteomyelitis is exceptionally rare.
Farhang Babamahmoodi   +3 more
doaj   +1 more source

Roving methyltransferases generate a mosaic epigenetic landscape and influence evolution in Bacteroides fragilis group

open access: yesNature Communications, 2023
Three types of DNA methyl modifications have been detected in bacterial genomes, and mechanistic studies have demonstrated roles for DNA methylation in physiological functions ranging from phage defense to transcriptional control of virulence and host ...
Michael J. Tisza   +6 more
doaj   +1 more source

Antimicrobial Resistance: the use of antimicrobials in the Livestock Sector [PDF]

open access: yes
The use of antimicrobials in livestock production provides a basis for improving animal health and productivity. This in turn contributes to food security, food safety, animal welfare, protection of livelihoods and animal resources.
Ferreira, J P   +3 more
core   +1 more source

Genotyping and antimicrobial resistance patterns of Escherichia coli O157 originating from cattle farms [PDF]

open access: yes, 2011
During a Escherichia coli O157 prevalence study on cattle farms, 324 E. coli O157 isolates were collected from 68 out of 180 cattle farms. All isolates harbored the eaeA gene and the enterohemolysin (ehxA) gene. The majority of the strains only contained
Boyen, Filip   +4 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Virulence and Antimicrobial Resistance Profiles of Salmonella enterica Serovars Isolated from Chicken at Wet Markets in Dhaka, Bangladesh

open access: yesMicroorganisms, 2021
Virulent and multi drug resistant (MDR) Salmonellaenterica is a foremost cause of foodborne diseases and had serious public health concern globally.
Nure Alam Siddiky   +8 more
doaj   +1 more source

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