Results 41 to 50 of about 410,913 (288)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Staphylococcus aureus ST764-SCCmecII high-risk clone in bloodstream infections revealed through national genomic surveillance integrating clinical data

Nature Communications
Antimicrobial resistance is a global health concern, and methicillin-resistant Staphylococcus aureus (MRSA) is one of the highest-priority organisms exhibiting this phenotype.
Junzo Hisatsune, Shoko Kutsuno, Yasuhisa Iwao, Kasumi Ishida-Kuroki, Koji Yahara, Norikazu Kitamura, Toshiki Kajihara, Shizuo Kayama, Yo Sugawara, Hiroki Kitagawa, Hiroki Ohge, Tomoyuki Mizukami, JARBS-SA Consortium, Takeshi Takahashi, Fumio Kawano, Motoyuki Sugai   +15 more
doaj   +1 more source

Molecular characterization and genetic relatedness of clinically Acinetobacter baumanii isolates conferring increased resistance to the first and second generations of tetracyclines in Iran

Annals of Clinical Microbiology and Antimicrobials, 2017
Background The increasing resistance of Acinetobacter baumannii to antibiotics has recently been regarded as a notable therapeutic difficulty. Evaluating resistance rates of some A.
Zahra Meshkat, Himen Salimizand, Yousef Amini, Mostafa Khakshoor, Davoud Mansouri, Hadi Farsiani, Kiarash Ghazvini, Adel Najafi   +7 more
doaj   +1 more source

Molecular Epidemiology of Plasmid-Mediated Types 1 and 3 Fimbriae Associated with Biofilm Formation in Multidrug Resistant Escherichia coli from Diseased Food Animals in Guangdong, China

Microbiology Spectrum, 2022
Types 1 and 3 fimbriae in Enterobacteriaceae play versatile roles in bacterial physiology including attachment, invasion, cell motility as well as with biofilm formation and urinary tract infections.
Wen-Ying Guo, Hui Zhang, Ming Cheng, Min-Rui Huang, Qian Li, Yu-Wei Jiang, Ji-Xing Zhang, Ruan-Yang Sun, Min-Ge Wang, Xiao-Ping Liao, Ya-Hong Liu, Jian Sun, Liang-Xing Fang   +12 more
doaj   +1 more source

Micropleated Nanofibrous Filters for High‐Efficiency Submicron Aerosol Filtration: A Comparative Study with Chemical, Biological, Radiological, and Nuclear Gas Mask Filters

Advanced Engineering Materials, EarlyView.
This study presents micropleated filters manufactured by needleless electrospinning. Nanofibers are deposited onto uniaxially pre‐stretched substrates that contract upon release, forming densely packed micropleats. This architecture increases effective surface area without enlarging the filter size, achieving quality factors comparable to those of ...
Aleksandr Fadeev, Kevin Crown, Sean Kinahan, Gabriel Lucero, Hayden Stromsodt, Svetlana Romanova, Yury Salkovskiy   +6 more
wiley   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Youth as change makers on antimicrobial resistance: an evidence-based call-to-action

Nature Communications
Youth represent un-tapped potential within the fight against antimicrobial resistance (AMR). This commentary describes the co-creation process of the Youth Manifesto on AMR which seeks to generate consensus on how equitable engagement of youth can be ...
Jessica Mitchell, Salman, F. Khan, Cristina Almazidou, Augusto Barón-Cruz, Randa A. Bazzi, Pablo Estrella-Porter, Nahashon, K. Gicheru, Karina Khatic, Michael, J. Mosha, Marina Ungurenci, Boama. E. P. Noali, Kalai Wong, Francesca Zanni   +12 more
doaj   +1 more source

Genomic characterization of extended-spectrum β-lactamase-producing Escherichia coli spread among chickens and healthy residents in Lombok, Indonesia

Applied and Environmental Microbiology
Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-Ec) poses a substantial public health challenge, particularly in developing countries where antimicrobial resistance is a growing concern.
Eustachius Hagni Wardoyo, Yo Sugawara, Satoshi Nakano, Hui Zuo, Shaheem Elahi, Chika Arai, Kohei Kondo, Kuntaman Kuntaman, Motoyuki Sugai   +8 more
doaj   +1 more source

Biosupercapacitors for Human‐Powered Electronics

Advanced Functional Materials, EarlyView.
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim, Seungho Baek, Woojung Jung, Hayeon Bae, Junyoung Mun, Yong Ho Kim, Sunkook Kim, Jung Ho Kim   +7 more
wiley   +1 more source

Removal of Steroid Hormone Micropollutants by an Electrochemical Carbon Nanotube Membrane Flow‐Through Reactor: Role of Concentration and Degradation Mechanisms

Advanced Functional Materials, EarlyView.
A flow‐through electrochemical membrane reactor equipped with a carbon nanotube membrane eliminates the mass transfer limitation, achieving removals >97.5% for steroid hormone (SH) micropollutants through electrochemical adsorption and degradation, over a broad initial concentration varying from 50 to 106 ng L−1.
Siqi Liu, David Jassby, Andrea I. Schäfer   +2 more
wiley   +1 more source