Results 111 to 120 of about 32,342 (271)

Creating a framework to align antimicrobial resistance (AMR) research with the global guidance: a viewpoint [PDF]

, 2022
Jessica Mitchell, Alex J. O’Neill, Rebecca King   +2 more
openalex   +1 more source

Arenaria serpyllifolia as a Natural Antiviolaceum Agent: Phytochemical, Biological, and Molecular Approaches

ChemistryOpen, EarlyView.
Arenaria serpyllifolia extract exhibits strong antioxidant, antimicrobial, antibiofilm, and antiquorum sensing activities. Key compounds, including levoglucosan and guanosine, show potent CviR receptor binding. Violacein inhibition and molecular dynamics confirm their stability, highlighting their potential as quorum sensing inhibitors and therapeutic ...
Meryem Burcu Külahcı, Betül Aydın, Emine Incilay Torunoğlu, Zekeriya Düzgün, Alper Durmaz, Erdi Can Aytar   +5 more
wiley   +1 more source

Evaluation of the Antioxidant, Anticancer, and Antibacterial Activities of Flower and Leaf Extracts of Chrysanthemum indicum

ChemistryOpen, EarlyView.
The tested methanolic extract of Chrysanthemum indicum flower and leaf is a rich source of bioactive molecules with significant antioxidant activity at low doses, potential anticancer effects at lower concentrations, and antimicrobial activities against Gram‐positive and Gram‐negative species, which is consistent with the plant's traditional ...
Tarad Abalkhail, Noorah A. Alkubaisi, Ibrahim M. Aziz, Mashail Fahad Alsayed, Hissah Abdulrahman Alodaini, Amal Saad AL‐Shenifi, Mohamed A. Farrag   +6 more
wiley   +1 more source

Deliverable D-IA.2.2.OH-Harmony-Cap.4.3 - Technical Report: Designing and Implementation of Harmonised Protocols for the Detection and Typing of Shiga toxin-producing Escherichia coli (STEC), Enterotoxigenic Escherichia coli (ETEC), Cryptosporidium and antimicrobial resistance (AMR) in Salmonella and Campylobacter spp. in the European Union [PDF]

, 2022
Rosangela Tozzoli, Mélanie Gay
openalex   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, EarlyView.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Operationalising a One Health approach to reduce the infection and antimicrobial resistance (AMR) burden in under-5 year old urban slum dwellers: The Childhood Infections and Pollution (CHIP) Consortium

, 2020
Logan Manikam, Yasmin Bou Karim, Yebeen Ysabelle Boo, Shereen Allaham, Ria Marwaha, Priti Parikh, Monica Lakhanpaul   +6 more
openalex   +1 more source

Moving From Point‐Based Analysis to Systems‐Based Modeling: Knowledge Integration to Address Antimicrobial Resistance

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Optimizing antibiotic therapy requires a holistic bench‐to‐bedside approach with interdisciplinary collaboration between pharmacologists, clinicians, microbiologists, and computational scientists. Novel experimental models provide insights into drug‐pathogen interactions within complex host environments, while multiomics data provide details ...
Bhavatharini Arun, Gauri G. Rao
wiley   +1 more source

Antimicrobial use and its association with the presence of methicillin-resistant staphylococci (MRS) and extended-spectrum beta-lactamases (ESBL)-producing coliforms in mastitic milk on dairy farms in the Chiba Prefecture, Japan

Heliyon, 2022
Food-producing animals, including dairy cattle, are potential reservoirs of antimicrobial resistance. However, there is limited data on antimicrobial use and the selection of resistant bacteria.
Masato Kikuchi, Takuma Okabe, Hideshige Shimizu, Takashi Matsui, Fuko Matsuda, Takeshi Haga, Kyoko Fujimoto, Yuko Endo, Katsuaki Sugiura   +8 more
doaj  

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source