Results 161 to 170 of about 189,957 (277)

AMR-Intervene: a social–ecological framework to capture the diversity of actions to tackle antimicrobial resistance from a One Health perspective [PDF]

, 2020
Anaïs Léger, Irene Lambraki, Tíscar Graells, Melanie Cousins, Patrik J. G. Henriksson, Stephan Harbarth, Carolee A. Carson, Shannon E. Majowicz, Max Troell, E. Jane Parmley, Peter Søgaard Jørgensen, Didier Wernli   +11 more
openalex   +1 more source

Real-time genomic surveillance for enhanced control of infectious diseases and antimicrobial resistance

Frontiers in Science
This article advocates for mobilizing pathogen genomic surveillance to contain and mitigate health threats from infectious diseases and antimicrobial resistance (AMR), building upon successes achieved by large-scale genome sequencing analysis of SARS-CoV-
Marc J. Struelens, Catherine Ludden, Guido Werner, V. Sintchenko, P. Jokelainen, Margaret Ip   +5 more
semanticscholar   +1 more source

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

ChemistryOpen, EarlyView.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri, Lavanya Khullar, Gobind Kumar, Sahil Mishra, Tamanna Dua, Vinay Singh, Kusum Harjai, Parvesh Singh, Vasundhara Singh   +8 more
wiley   +1 more source

Focus areas for the forward momentum of sub-national action plans on antimicrobial resistance (AMR) - Perspectives from three states in a Low- and middle-income Country [PDF]

, 2023
Jasmine Ruth Baluja, Jaya Ranjalkar, Philip Mathew, Sujith J Chandy, Raghini Ranganathan, Shruthi Anna Thomas   +5 more
openalex   +1 more source

Antimicrobial Resistance (AMR) and Multidrug Resistance (MDR): Overview of Current Approaches, Consortia and Intellectual Property Issues [PDF]

, 2017
The supply of new diagnostics and treatments is insufficient to keep up with the increase in antimicrobial resistance (AMR) and multidrug resistance (MDR) as older medicines are used more widely and microbes develop resistance to them.
Bhagwandin, Niresh, Jenner, Andrew, Kowalski, Stanley P.   +2 more
core   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Promoting Sustainability in an Aging City: Drivers of Proper Pharmaceuticals Disposal

Sustainable Development, EarlyView.
ABSTRACT In a demographic context marked by a rapid increase in the older adult population, pharmaceutical residues represent an increasing threat to sustainability. Promoting the proper disposal of this waste by households is fundamental in attaining the SDGs, particularly SDG 8. This paper assesses the determinants influencing household participation
Fernando Arbués, Roberto Balado‐Naves, Inmaculada Villanúa   +2 more
wiley   +1 more source

Multifunctional Nanoscale Pigments: Emerging Risks and Circular Strategies for a Sustainable Future

Small Science, EarlyView.
The growing use of nanoscale pigments drives innovation across sectors, yet raises environmental and health concerns. This article explores their multifunctional roles, emerging risks, and regulatory gaps through a One Health lens. It highlights sustainable strategies—including benign‐by‐design approaches and circular economy principles—crucial for ...
Ajay Vikram Singh, Preeti Bhardwaj, Vimal Kishore, Sunil Choudhary, Akihiko Hirose, Neha Gupta, Madleen Busse, Swarn Lata Singh, Christopher J. Osgood   +8 more
wiley   +1 more source

Amphiphile‐Assisted Synthesis of Ruthenium Nanoparticles for Controlled Release and Enhanced Antibacterial Activity

Small Methods, EarlyView.
A novel synthesis of Ruthenium nanoparticles (RuNPs) based on amphiphiles and Ru(III) complexes as antibacterial agents with controlled release properties has been developed. Post‐synthesis modification of the RuNPs with PEG molecular staples enables controlled Ru release, reducing the burst effect.
Raúl Gimeno‐Ferrero, Manel Estruch‐Blasco, Eloísa Pajuelo, Inmaculada Fernández, María L. García‐Martín, Manuel Pernia Leal   +5 more
wiley   +1 more source

Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens

Small Structures, EarlyView.
Applications of DNA origami nanostructures in pathogen detection and antimicrobial drug delivery require their efficient and robust binding to bacterial cells. Here, the cell wall‐binding glycopeptide antibiotic vancomycin is conjugated to selected staple strands and displayed in multivalent arrangements on the DNA origami surface to facilitate the ...
Özge Coşkuner Leineweber, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann, Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, Adrian Keller   +8 more
wiley   +1 more source