Results 61 to 70 of about 2,545,245 (294)

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

Advanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka, Bushra Raahat, Spyros Tragoudas, Hui Li   +3 more
wiley   +1 more source

System-wide approaches to antimicrobial therapy and antimicrobial resistance in the UK: the AMR-X framework [PDF]

Antimicrobial resistance (AMR) threatens human, animal, and environmental health. Acknowledging the urgency of addressing AMR, an opportunity exists to extend AMR action-focused research beyond the confines of an isolated biomedical paradigm.
Armstrong-James, Darius, Carrol, Enitan, Agnew, Emily, Brown, Colin, Pouwels, Koen, Clements, Michelle, Dane, Aaron, Ashfield, Thomas, Barlow, Gavin, Cooke, Graham, Hayward, Gail, Abel, Kathryn, Armstrong, Natalie, Rahman, Najib, Bielicki, Julia, Baillie, J Kenneth, Walker, Ann Sarah, Aston, Stephen, Amos, James, Baldwin, Steven, Day, Jeremy, Bartle, Victoria, Dark, Paul, Eyre, David   +23 more
core   +4 more sources

Antimicrobial resistance surveillance in the South African private sector report for 2016

Southern African Journal of Infectious Diseases, 2018
Aim: The relevance of surveillance for antimicrobial resistance is increasingly recognised in the light of a global action plan to combat resistance.
Olga Perovic, Husna Ismail, Erika Van Schalkwyk, Warren Lowman, Elizabeth Prentice, Marthinus Senekal, Chetna N. Govind   +6 more
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Effect on Antimicrobial Resistance of a Policy Restricting Over-the-Counter Antimicrobial Sales in a Large Metropolitan Area, São Paulo, Brazil

Emerging Infectious Diseases, 2022
Although restricting over-the-counter (OTC) antimicrobial drug sales is recommended globally, no data track its effect on antimicrobial resistance (AMR) in bacteria.
Maria L. Moura, Icaro Boszczowski, Manuela Blaque, Rafael M. Mussarelli, Victor Fossaluza, Ligia C. Pierrotti, Gustavo Campana, Maria C. Brandileone, Rosemeire Zanella, Samanta C.G. Almeida, Anna S. Levin   +10 more
doaj   +1 more source

Antimicrobial Resistance: Techniques to Fight AMR in Bacteria – A Review [PDF]

Antimicrobials or antibiotics were the important revelations of the last century, however, it came along with a silent curse that people care less to talk about.
Megala Jayaraman, Ernessto Mahizhchi, Diveyaa Sivakumar   +2 more
core   +1 more source

Comparative Meta‐Analysis of Antimicrobial Peptides in Aquatic and Terrestrial Livestock Species

Animal Research and One Health, EarlyView.
A global meta‐analysis of 58 studies (926 effect sizes and 29 species across five taxa) revealed that dietary antimicrobial peptides generally improve growth performance, blood metabolites, and immune responses. The greatest benefits were observed in omnivorous livestock, such as pigs and chickens. Dose‐duration effects were evident. An optimal outcome
Lily Liu, Xu Luo, Qin Zhang, Jinhai Wang, Alan E. Wilson   +4 more
wiley   +1 more source

Bioluminescent Pseudomonas aeruginosa and Escherichia coli for whole-cell screening of antibacterial and adjuvant compounds

Scientific Reports
Continued efforts to discover new antibacterial molecules are critical to achieve a robust pre-clinical pipeline for new antibiotics. Screening of compound or natural product extract libraries remains a widespread approach and can benefit from the ...
Eszter Farkas, Geoffrey A. McKay, Lin Tao Hu, Mina Nekouei, Peying Ho, Wilfried Moreira, Chia Ching Chan, Linh Chi Dam, Karine Auclair, Samantha Gruenheid, Lyle Whyte, Peter Dedon, Dao Nguyen   +12 more
doaj   +1 more source

Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia

Frontiers in Cellular and Infection Microbiology, 2019
Objective: To undertake the first detailed genomic analysis of methicillin-resistant Staphylococcus aureus (MRSA) isolated in Sri Lanka.Methods: A prospective observational study was performed on 94 MRSA isolates collected over a 4 months period from the
Sharla M. McTavish, Sarah J. Snow, Ellie C. Cook, Bruno Pichon, Sarah Coleman, Geoffrey W. Coombs, Stanley Pang, Cesar A. Arias, Cesar A. Arias, Cesar A. Arias, Lorena Díaz, Lorena Díaz, Emma Boldock, Emma Boldock, Steve Davies, Mangala Udukala, Angela Marie Kearns, Sisira Siribaddana, Sisira Siribaddana, Thushan I. de Silva, Thushan I. de Silva   +20 more
doaj   +1 more source

Estimation of the impact of hospital-onset SARS-CoV-2 infections on length of stay in English hospitals using causal inference

BMC Infectious Diseases, 2022
Background From March 2020 through August 2021, 97,762 hospital-onset SARS-CoV-2 infections were detected in English hospitals. Resulting excess length of stay (LoS) created a potentially substantial health and economic burden for patients and the NHS ...
James Stimson, Koen B. Pouwels, Russell Hope, Ben S. Cooper, Anne M. Presanis, Julie V. Robotham   +5 more
doaj   +1 more source