Results 71 to 80 of about 187,271 (262)

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Antimicrobial resistance profile and prevalence of tetracycline resistance genes in Escherichia coli isolates from broiler chickens, northwestern Iran [PDF]

Bulgarian Journal of Veterinary Medicine, 2018
Frequencies of tetracycline resistance genes (tetA, and tetB), and antimicrobial resistance profile of Escherichia coli isolated from broilers of West Azerbaijan province were investigated.
V.Mohammadi, A.Ghaniei , P. Sepehrnia
doaj   +1 more source

Gene Exploration and Analysis in Antimicrobial Resistance

, 2022
Antimicrobial genes (AMR) are today classified as a global burden causing up to 4.95 million associated deaths in 2019. The impact these bacterial genes have on humanity makes in depth analysis and information gathering highly relevant for mastering and decreasing these genes’ spread.
Shahoon Hossein Abadi, Mona, Thelin, Christopher, Westerberg, Sten Johan, Widén, Erik   +3 more
openaire   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Does Shiga Toxin-Producing Escherichia coli and Listeria monocytogenes Contribute Significantly to the Burden of Antimicrobial Resistance in Uruguay?

Frontiers in Veterinary Science, 2020
Shiga toxin-producing Escherichia coli (STEC) and Listeria monocytogenes are worldwide recognized zoonotic pathogens. Recent reports have emerged about the circulation of antimicrobial-resistant STEC and L. monocytogenes isolates. To assess the frequency
María Inés Mota, Sylvia Vázquez, Cecilia Cornejo, Bruno D'Alessandro, Valeria Braga, Ana Caetano, Laura Betancor, Laura Betancor, Gustavo Varela   +8 more
doaj   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Acquired Antimicrobial Resistance Genes of Escherichia coli Obtained from Nigeria: In silico Genome Analysis

Journal of Food Quality and Hazards Control, 2021
Background: Antimicrobial resistance is a global problem with enormous public health and economic impact. This study was carried out to get an overview of acquired antimicrobial resistance gene sequences in the genomes of Escherichia coli isolated from ...
O. Nwaiwu, H. Onyeaka
doaj  

Bacterial gene loss as a mechanism for gain of antimicrobial resistance

Current Opinion in Microbiology, 2012
يمثل الحصول على الحمض النووي الخارجي من قبل البكتيريا المسببة للأمراض الأساس لكثير من مقاومة مضادات الميكروبات المكتسبة في البكتيريا المسببة للأمراض. تتمثل الآلية الأكثر تطرفًا لتجنب تأثير المضادات الحيوية في حذف هدف الدواء، على الرغم من أنه من المتوقع أن يكون هذا نادرًا لأن أهداف الدواء غالبًا ما تكون جينات أساسية.
M. Estée Török, Narisara Chantratita, Sharon J. Peacock   +2 more
openaire   +2 more sources