Results 41 to 50 of about 82,129 (320)

Current state of antimicrobial stewardship in children’s hospital emergency departments [PDF]

, 2017
BACKGROUND Antimicrobial stewardship programs (ASPs) effectively optimize antibiotic use for inpatients; however, the extent of emergency department (ED) involvement in ASPs has not been described.
Dayan, Peter S, Gerber, Jeffrey S, Hersh, Adam L, Kuppermann, Nathan, May, Larissa, Mistry, Rakesh D, Newland, Jason G, Perman, Sarah M   +7 more
core   +2 more sources

The effect of Meropenem stewardship at Prof Ngoerah Hospital on the prevalence of carbapenem resistant Acinetobacter baumannii, Carbapenem-resistant Pseudomonas aeruginosa and the cost of purchasing meropenem

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Irrational use of antibiotics will trigger anti-microbial resistance which is a threat to health problems now and in the future. The use of meropenem is often the last choice in using antibiotics without undergoing microbiological examination
Made Susila Utama, Reza Andriani, Wayan Suranadi, Dwi Fatmawati   +3 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Clostridium difficile infection in the United States: A national study assessing preventive practices used and perceptions of practice evidence [PDF]

, 2015
We surveyed 571 US hospitals about practices used to prevent Clostridium difficile infection (CDI). Most hospitals reported regularly using key CDI prevention practices, and perceived their strength of evidence as high.
Dubberke, Erik R, Flanders, Scott A, Fowler, Karen E, Greene, M. Todd, Krein, Sarah L, Ratz, David, Saint, Sanjay   +6 more
core   +2 more sources

Antimicrobial Stewardship Programme [PDF]

JAC-Antimicrobial Resistance, 2019
Graphical Abstract.
openaire   +2 more sources

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Frequency, lethality, and demographic trends of acute respiratory viruses in hospitalized patients: insights from a German tertiary care hospital from july 2022 to april 2023

BMC Infectious Diseases
Background Acute respiratory infections (ARI) exhibit varying lethality rates, influenced by individual and population factors. This retrospective study aimed to analyse infection frequency, clinical characteristics, and factors associated with lethality
Juliane Mees, Michael Eisenmann, Anna Höhn, Sina Ebert, Tamara Pscheidl, Nina Roth, Gülmisal Güder, Nils Petri, Isabell Wagenhäuser, Manuel Krone   +9 more
doaj   +1 more source

Efficacy of a Disinfectant in Reducing Pathogen Contamination in Renovated Inpatient In-Room Sinks: A Randomized Controlled Trial

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: The prevention of colonization of new inpatient room sinks with epidemiologically important pathogen (EIP) is poorly understood. Methods: We performed a randomized controlled trial and microbiological analysis to describe the timing and ...
Bobby Warren, Amanda Graves, Guerbine Fils-aime, Aaron Barrett, Isadora Mamikunian, Becky Smith, Deverick Anderson   +6 more
doaj   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source