Results 71 to 80 of about 78,126 (264)

What are the ‘active ingredients’ of interventions targeting the public's engagement with antimicrobial resistance and how might they work? [PDF]

, 2018
Objectives. Changing public awareness of antimicrobial resistance (AMR) represents a global public health priority. A systematic review of interventions that targeted public AMR awareness and associated behaviour was previously conducted.
Davis, Mark, Flowers, Paul, Gozdzielewska, Lucyna, Langdridge, Darren, MacDonald, Jennifer, McParland, Joanna L., Price, Lesley, Smith, Fraser, Williams, Lynn, Young, Mairi   +9 more
core   +4 more sources

The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study. [PDF]

, 2020
BACKGROUND: In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common infections in children and adults.
Berger, C, Bielicki, JA, Bornand, D, Füri, J, Huttner, B, Widmer, A   +5 more
core   +3 more sources

Tackling Staph: Reducing Staphylococcus aureus Colonization in a College Football Team

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: Athletes in contact sports have a higher rate of Staphylococcus aureus nasal carriage than the general population, leading to an increased risk of skin and soft tissue infections (SSTIs).
Jessica Seidelman, Erin Gettler, Aaron Barrett, Bobby Warren, Hap Zarzour, Connor Warren, Jeffrey Bytomski, Nicholas Potter, Becky Smith, Deverick Anderson   +9 more
doaj   +1 more source

Susceptibility Provision Enhances Effective De-escalation (SPEED): utilizing rapid phenotypic susceptibility testing in Gram-negative bloodstream infections and its potential clinical impact [PDF]

, 2019
Objectives We evaluated the performance and time to result for pathogen identification (ID) and antimicrobial susceptibility testing (AST) of the Accelerate Pheno™ system (AXDX) compared with standard of care (SOC) methods.
Blevins, Sarah, Bocian, Brittany, Davis, Thomas E., Desai, Armisha, Emery, Christopher L., Hiles, Jon, Manaloor, John J., Schmitt, Bryan H., Schneider, Jack G., Smith, Nathan W., Wood, James B., Wrin, Justin   +11 more
core   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

A baseline assessment of antimicrobial stewardship core element implementation in selected public hospitals in Malawi: findings from the 2023 National Program Audit

Frontiers in Public Health
BackgroundAntimicrobial resistance (AMR) is a significant global health challenge, particularly in low- and middle-income countries (LMICs). In Malawi, frequent stockouts of essential medicines and the widespread dispensing of antibiotics without ...
Ronald Chitatanga, Ronald Chitatanga, Chikhulupiliro Yiwombe, Chikhulupiliro Yiwombe, Oscar Divala, Mwayi Prudence Msokera, Ellen Banda, Ellen Banda, Hope Chadwala, Manuel Wellington Gilmon, Wezi Kaminyoghe, Innocent Chibwe, Innocent Chibwe, Harry Milala, Harry Milala, Alinafe Kawerama, Alinafe Kawerama, Kenneth Nyoni, Chikumbutso Mpanga, Christina Mwinjiwa, Akuzike Makondesa, Maurice Mwehiwa, Donald Mlombwa, Daniel Namalawe, Silver Benito, Emmie Jingini, Evelyn Wesangula, Martin Matu, Emily Ciccone, Robert Krysiak, Collins Mitambo, Titha Dzowela   +31 more
doaj   +1 more source

Metronidazole resistance: a hidden epidemic? [PDF]

, 2018
This is a personal reflection from working as a clinical microbiologist and becoming increasingly concerned over gaps in our knowledge of metronidazole resistance and its impact on clinical ...
Smith, Andrew
core   +1 more source

Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative

Journal of Hospital Medicine, EarlyView.
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski, Karen Howard, Hannah Imlay, Chaorong Wu, Christy L. Hopkins, Valerie M. Vaughn, Emily S. Spivak   +6 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria [PDF]

, 2020
Background Antimicrobial resistance (AMR) compromises the treatment of patients with serious infections in intensive care units (ICUs), and intensive care physicians are increasingly facing patients with bacterial infections with limited or no adequate ...
De Waele, Jan, Friggeri, Arnaud, Garnacho-Montero, José, Gustin, Marie Paule, Jean, Astrid, Kohlenberg, Anke, Lepape, Alain, Monnet, Dominique L., Savey, Anne, Vanhems, Philippe   +9 more
core   +2 more sources