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Antimicrobial therapy of leptospirosis

Current Opinion in Infectious Diseases, 2006
Leptospirosis is an important but often overlooked zoonotic disease that can cause significant morbidity and mortality. The optimal antimicrobial treatment for this disease has not been established. This review summarizes the most recent literature pertaining to the use of antimicrobial agents in the treatment of leptospirosis.Leptospira are highly ...
Matthew E, Griffith   +2 more
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Antimicrobial Therapy for Shigellosis

Clinical Infectious Diseases, 1991
In controlled clinical trials, which were first performed with use of the sulfonamides, antimicrobial agents have been shown to shorten the duration of symptoms and lessen the excretion of pathogens during episodes of shigellosis. Not all antimicrobial agents that are active in vitro against Shigella are effective in vivo, and efficacy of an agent can ...
M A, Salam, M L, Bennish
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Antimicrobial Therapy

Clinics in Geriatric Medicine, 1992
Antibiotic dosing is not influenced by age as much as by the weight loss and loss of renal function that occurs with advanced age. The chronic diseases that afflict the frail, elderly person, however, exert a profound influence on the types of infections and the variety of organisms that must be considered in empiric therapy choices.
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ANTIMICROBIAL THERAPY IN THE ELDERLY

Medical Clinics of North America, 2001
This article focuses on the special characteristics of infection in the elderly and provides an update of the principles of antibiotic selection, use of specific antibiotics, and empiric use of antimicrobials in the treatment of infectious diseases in this particularly vulnerable group.
S, Rajagopalan, T T, Yoshikawa
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Antimicrobial therapy in Dermatology

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2006
SummaryThe extensive and sometimes indiscriminate use of antibiotics sometimes without strict indications has led to increases in both bacterial resistance and sensitization of patients. Systemic antibiotics in skin infections are indicated when a severe local infection occurs which spreads into the surrounding tissue or when there are signs of ...
Cord, Sunderkötter   +2 more
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Pharmacoeconomics of antimicrobial therapy

American Journal of Health-System Pharmacy, 1999
Switch therapy, sequential therapy, and step-down therapy are discussed in terms of their contribution to reducing antimicrobial expenditures. Pharmacoeconomics is the science used to identify and compare the costs and consequences of drug therapy in terms of efficacy, safety, and overall health care.
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Principles of Antimicrobial Therapy

Veterinary Clinics of North America: Small Animal Practice, 1998
It has been 2500 years since the Chinese began applying moldy soybean curd to cure skin infections. Technology today has refined the benefits of antibiotic-forming molds and bacteria and has greatly increased the number of antimicrobial drugs available to combat infection.
T, Whittem, D, Gaon
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Combination Antimicrobial Therapy

Pediatric Clinics of North America, 1983
In spite of a large volume of data regarding the in vitro activity of single and combined antimicrobial activity, the clinical relevance of these studies is unclear. Few comparative trials of combined and single antibiotic therapy of human infection have been performed.
D M, Shlaes, S N, Bass
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