Results 191 to 200 of about 15,310,413 (304)

Impact of a Multifaceted Antimicrobial Stewardship Program on Antimicrobial Use and Prescription Quality in a Pediatric Intensive Care Unit: An Interrupted Time-Series Study. [PDF]

Antibiotics (Basel)
Fernández-Vallespin L, Fresán-Ruiz E, López-Ramos MG, Pieras-López Á, Velasco-Arnaiz E, Jordan I.   +5 more
europepmc   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Correction to: Standardizing Antimicrobial Use in a Resource-Limited Pediatric Surgical Unit in Botswana. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Standardizing Antimicrobial Use in a Resource-Limited Pediatric Surgical Unit in Botswana. [PDF]

Open Forum Infect Dis
Bedada AG, Rankin M, Steenhoff AP, Kitt E.   +3 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

National Antimicrobial Stewardship Performance and Antimicrobial Use in Saudi Ministry of Health Hospitals: A Four-Year Multicenter Surveillance Analysis, 2021-2024. [PDF]

Antibiotics (Basel)
Alghamdi S, Algarni M, Mutlaq A, Almuraybidh R, Alfardus N, Aljudaibi S, Aljaffar A, Alghamdi A, Alghamdi S, Alshammari AS, Alzahrani AA, Barakat BM, Albanghali MA.   +12 more
europepmc   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Strategies for Reducing Antimicrobial Use in Cattle Through Gut Microbiome Modulation: A Systematic Review of Alternatives to Antibiotics. [PDF]

Animals (Basel)
Ntsongota Z, Ikusika OO, Mndela M, Jaja IF.   +3 more
europepmc   +1 more source

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

Advanced Science, EarlyView.
A new class of Cu, Ni bimetallic 2D cMOF (CuNi‐HHTP 2D cMOF) featuring dual catalytic sites and high delocalized electronic structure for boosting POD performance. The CuNi‐HHTP 2D‐cMOF enhances the conversion kinetics of H2O2 to ROS, which subsequently enhances antibacterial activity and accelerates the healing of oral ulcers, with macroscopic wound ...
Yixuan Lu, Qinqin Li, Yumin Chen, Shihan Zhang, Shuai Ding, Yanpei Wang, Youxing Liu, Yaru Guo, Xuliang Deng, Shaojun Guo   +9 more
wiley   +1 more source

What will it take for behavior to change? Findings from a baseline evaluation of an intervention to reduce antimicrobial use among smallholder poultry farmers in Zimbabwe. [PDF]

Front Vet Sci
Mushanawani PC, Mavhu W, Majuru CS, Hodobo CT, Gurira TN, Waniwa E, Nyoka K, Maparo G, Wasarirevu, Mubvuta J, Mutengwa I, Zvorufura P, Madzivanyika T, Phiri M, Charumbira T, Westwood E, von Humboldt-Scotland S, Ventura-Gabarró C, Zaman AW.   +18 more
europepmc   +1 more source