Results 1 to 10 of about 1,829,235 (358)

Evaluation of Dilution Susceptibility Testing Methods for Aztreonam in Combination with Avibactam against Enterobacterales

Microbiology Spectrum, 2022
As multidrug and pan-resistance among Enterobacterales continue to increase, there is an urgent need for more therapeutic options to treat these infections.
C. J. Kelley, A. Kennedy-Mendez, O. N. Walser, M. T. Thwaites, F. F. Arhin, C. M. Pillar, D. A. Hufnagel   +6 more
doaj   +1 more source

A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database

Microbiology Spectrum, 2023
Resistance-modifying agents have been historically underrepresented in the Comprehensive Antibiotic Resistance Database (CARD). In the process of curating over 60 new molecules into CARD’s Antibiotic Resistance Ontology, the limitations of current ...
Keaton W. Smith, Brian P. Alcock, Shawn French, Maya A. Farha, Amogelang R. Raphenya, Eric D. Brown, Andrew G. McArthur   +6 more
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Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Antimicrobial Resistance and Infection Control, 2022
Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman, Elizabeth Temkin, Liat Wulffhart, Amir Nutman, Vered Schechner, Pnina Shitrit, Racheli Shvartz, Mitchell J. Schwaber, Yehuda Carmeli   +8 more
doaj   +1 more source

Discovery of a novel integron-borne aminoglycoside resistance gene present in clinical pathogens by screening environmental bacterial communities

Microbiome, 2020
Background New antibiotic resistance determinants are generally discovered too late, long after they have irreversibly emerged in pathogens and spread widely.
Maria-Elisabeth Böhm, Mohammad Razavi, Nachiket P. Marathe, Carl-Fredrik Flach, D. G. Joakim Larsson   +4 more
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A framework for identifying the recent origins of mobile antibiotic resistance genes

Communications Biology, 2021
Ebmeyer and colleagues developed a genomic framework for identification and scrutiny of the origins of antibiotic resistance genes. Using data scoured from the literature and publicly available genomes, their results indicate that only 81% of previously ...
Stefan Ebmeyer, Erik Kristiansson, D. G. Joakim Larsson   +2 more
doaj   +1 more source

Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance

Microbiome, 2020
Background The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Kihyun Lee, Dae-Wi Kim, Do-Hoon Lee, Yong-Seok Kim, Ji-Hye Bu, Ju-Hee Cha, Cung Nawl Thawng, Eun-Mi Hwang, Hoon Je Seong, Woo Jun Sul, Elizabeth M. H. Wellington, Christopher Quince, Chang-Jun Cha   +12 more
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Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance

Canadian Journal of Infectious Diseases and Medical Microbiology, 2005
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
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A Novel, Integron-Regulated, Class C β-Lactamase

Antibiotics, 2020
AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-
Maria-Elisabeth Böhm, Mohammad Razavi, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source

The Association between Insertion Sequences and Antibiotic Resistance Genes

mSphere, 2020
Insertion sequences (ISs) are abundant mobile genetic elements on bacterial genomes, responsible for mobilization of many genes, including antibiotic resistance genes (ARGs).
Mohammad Razavi, Erik Kristiansson, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source

EQUITABLE ACCESS

International Journal of Infectious Diseases, 2023
The COVID-19 epidemic has once again highlighted the challenges to achieve equitable access to critical antimicrobials and vaccines. The problem is particularly acute for antimicrobials.Despite recent investments improving the pipeline for new treatments,
Manica Balasegaram, Jennifer Cohn
doaj   +1 more source